弱内向整流钾通道Kir4.1（KCNJ10）在前包钦格复合体中的可能作用。
Possible roles of the weakly inward rectifying k+ channel Kir4.1 (KCNJ10) in the pre-Bötzinger complex.
作者信息
Papadopoulos Nestoras, Winter Stefan M, Härtel Kai, Kaiser Melanie, Neusch Clemens, Hülsmann Swen
机构信息
Department of Neuro- and Sensory Physiology, Georg-August-University Göttingen, 37073 Göttingen, Germany.
出版信息
Adv Exp Med Biol. 2008;605:109-13. doi: 10.1007/978-0-387-73693-8_19.
Rhythmic activity of respiratory neurons is dependent on the clearance of neurotransmitter by astrocytes. Astrocytes should also be involved in the permanent and rapid clearance of extracellular ions. We analyzed the expression of the weakly inwardly rectifying K+ channel Kir4.1 (KCNJ10) in the respiratory network and studied the possible functions for neuronal activity in the pre-Bötzinger complex.
呼吸神经元的节律性活动依赖于星形胶质细胞对神经递质的清除。星形胶质细胞还应参与细胞外离子的持续快速清除。我们分析了呼吸网络中弱内向整流钾通道Kir4.1（KCNJ10）的表达，并研究了其在前包钦格复合体中对神经元活动的可能作用。
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