Abbas S M, Hill A G
Department of Surgery, Middlemore Hospital, University of Aukland, Auckland, New Zealand.
Anaesthesia. 2008 Jan;63(1):44-51. doi: 10.1111/j.1365-2044.2007.05233.x.
The use of intra-operative Doppler oesophageal probes provides continuous monitoring of cardiac output. This enables optimisation of intravascular volume and tissue perfusion in major abdominal surgery, which is thought to reduce postoperative complications and shorten hospital stay. Medline and EMBASE were searched using the standard methodology of the Cochrane collaboration for trials that compared oesophageal Doppler monitoring with conventional clinical parameters for fluid replacement in patients undergoing major elective abdominal surgery. Data from randomised controlled trials were entered and analysed in Meta-view in Rev-Man 4.2 (Nordic, Denmark). We included five studies that recruited 420 patients undergoing major abdominal surgery who were randomly allocated to receive either intravenous fluid treatment guided by monitoring ventricular filling using oesophageal Doppler monitor or fluid administration according to conventional parameters. Pooled analysis showed a reduced hospital stay in the intervention group. Overall, there were fewer complications and ICU admissions, and less requirement for inotropes in the intervention group. Return of normal gastro-intestinal function was also significantly faster in the intervention group. Oesophageal Doppler use for monitoring and optimisation of flow-related haemodynamic variables improves short-term outcome in patients undergoing major abdominal surgery.
术中使用多普勒食管探头可对心输出量进行连续监测。这有助于在大型腹部手术中优化血管内容量和组织灌注,据认为这可减少术后并发症并缩短住院时间。按照Cochrane协作网的标准方法检索了Medline和EMBASE,以查找比较食管多普勒监测与传统临床参数用于择期大型腹部手术患者液体补充的试验。将随机对照试验的数据录入Rev-Man 4.2(丹麦北欧公司)的Meta-view中进行分析。我们纳入了五项研究,这些研究招募了420例接受大型腹部手术的患者,他们被随机分配接受以下两种治疗之一:一种是使用食管多普勒监测仪监测心室充盈情况来指导静脉输液治疗,另一种是根据传统参数进行液体输注。汇总分析显示干预组的住院时间缩短。总体而言,干预组的并发症和入住重症监护病房的情况较少,对血管活性药物的需求也较少。干预组胃肠道功能恢复正常的速度也明显更快。使用食管多普勒监测和优化与血流相关的血流动力学变量可改善接受大型腹部手术患者的短期预后。