Park C S, Chung H C, Lim H Y, Kim D L, Koh E H, Kim J H, Roh J K, Chun S I, Yang W I, Kim G E
Yonsei Med J. 1991 Dec;32(4):362-9. doi: 10.3349/ymj.1991.32.4.362.
Within the past few years, an increasing number of reports of Hodgkin's disease following the diagnosis of, and frequently coexisting with, mycosis fungoides have appeared. Previously, Hodgkin's disease found in the lymph nodes of the patient diagnosed as mycosis fungoides was considered as a transformed form of the mycosis fungoides. But, now it has been proven that Hodgkin's disease and mycosis fungoides are histologically and immunohistochemically distinct disease entities. We report a well-documented case of a man who developed Hodgkin's disease and mycosis fungoides simultaneously as a composite lymphoma. Our case emphasizes the importance of considering the diagnosis of another lymphoma in patients with mycosis fungoides who have lymphadenopathy. The cutaneous mycosis fungoides and the Hodgkin's disease should be treated as an independent disease.
在过去几年中,越来越多关于蕈样肉芽肿诊断后发生霍奇金病且二者常并存的报告出现。以前,在被诊断为蕈样肉芽肿的患者淋巴结中发现的霍奇金病被认为是蕈样肉芽肿的一种转化形式。但是,现在已经证实霍奇金病和蕈样肉芽肿在组织学和免疫组织化学上是不同的疾病实体。我们报告一例有充分记录的病例,一名男性同时发生霍奇金病和蕈样肉芽肿,形成复合性淋巴瘤。我们的病例强调了对于有淋巴结病的蕈样肉芽肿患者考虑诊断为另一种淋巴瘤的重要性。皮肤蕈样肉芽肿和霍奇金病应作为独立疾病进行治疗。