Khan Shahid M, Sallehuddin Ahmad Bin, Al-Bulbul Ziad R, Al-Halees Zohair Y
King Faisal Heart Institute, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Ann Thorac Surg. 2008 Jan;85(1):179-84. doi: 10.1016/j.athoracsur.2007.07.012.
We sought to identify the prevalence of bicuspid pulmonary valve among patients with transposition of the great arteries undergoing the arterial switch operation and evaluate functional integrity of that valve in the neoaortic position.
Between October 1985 and December 2001, 391 patients had an arterial switch operation for transposition and its variants. Perioperative information and follow-up data were available for 342 patients. The serial echocardiograms of patients with bicuspid pulmonary valve were reviewed. The neoaortic valve was serially assessed, focusing on aortic insufficiency, annulus diameter, and pressure gradients.
Twenty-four patients (7%) had a bicuspid pulmonary valve. Age at operation was 5 days to 12 years. Two patients were lost to follow up, and 22 patients had mean follow-up of 5.3 years (range, 2 months to 13 years), of which 21 patients were alive and 1 died late. At least two postoperative echocardiogram reports were available on 19 patients. Seven patients had no neoaortic regurgitation, and 10 had trivial regurgitation. Severe aortic regurgitation developed in 1 patient with endocarditis and in another with repair of Taussig-Bing anomaly. Neoaortic valve size indexed to body surface area showed an increase in annular diameter over time proportional to somatic growth. No significant valve stenosis developed.
Encountering a bicuspid pulmonary valve at the time of an arterial switch operation is not uncommon. The integrity of a bicuspid pulmonary valve in the neoaortic position is maintained at a mean follow-up of 5.3 years. We believe that the presence of a bicuspid pulmonary valve is not a contraindication to an arterial switch operation.
我们试图确定在接受动脉调转术的大动脉转位患者中,二叶式肺动脉瓣的患病率,并评估该瓣膜在新主动脉位置的功能完整性。
1985年10月至2001年12月期间,391例患者接受了针对大动脉转位及其变异型的动脉调转术。342例患者有围手术期信息和随访数据。对二叶式肺动脉瓣患者的系列超声心动图进行了回顾。对新主动脉瓣进行了系列评估,重点关注主动脉瓣关闭不全、瓣环直径和压力阶差。
24例患者(7%)有二叶式肺动脉瓣。手术年龄为5天至12岁。2例患者失访,22例患者平均随访5.3年(范围2个月至13年),其中21例存活,1例晚期死亡。19例患者至少有两份术后超声心动图报告。7例患者无新主动脉瓣反流,10例有轻度反流。1例心内膜炎患者和另1例法洛四联症修复患者发生了严重主动脉瓣反流。以体表面积计算的新主动脉瓣大小显示,瓣环直径随时间增加,与身体生长成正比。未发生明显的瓣膜狭窄。
在动脉调转术时遇到二叶式肺动脉瓣并不罕见。在平均5.3年的随访中,二叶式肺动脉瓣在新主动脉位置的完整性得以维持。我们认为,二叶式肺动脉瓣的存在并非动脉调转术的禁忌证。