Kostas Theodoros T, Ioannou Christos V, Veligrantakis Michalis, Pagonidis Constantinos, Katsamouris Asterios N
Vascular Surgery Department, University Hospital of Heraklion, University of Crete Medical School, Heraklion, Crete, Greece.
J Vasc Surg. 2007 Dec;46(6):1234-41. doi: 10.1016/j.jvs.2007.07.055.
To investigate the effect of stripping the below knee great saphenous vein (GSV) segment on varicose vein recurrence as well as any disability induced after saphenous nerve injury (SNI) during a 5-year period.
One hundred and six limbs (86 patients, 64 female, mean age 46 years), that underwent GSV stripping, to the knee or ankle level, were prospectively followed up at 1 month and 5 years postoperatively with clinical examination and color duplex imaging (CDI), in order to evaluate SNI and the development of recurrence. The extent of GSV stripping complied with preoperative CDI in 84 limbs (79%) that were subjected to GSV stripping to the ankle and full abolishment of duplex-confirmed reflux. Furthermore, 19 limbs (18%) underwent stripping restricted to the below knee level since the distal GSV was competent. On the contrary, in three limbs (3%), the extent of stripping did not comply with preoperative CDI due to the absence of varicosities in the tibia, and stripping was restricted to the knee level, although they had reflux along the whole GSV length.
Overall recurrence was found in 24 out of 106 operated limbs (23%) after 5 years. Recurrence was found to be 20% (17/84) in the limbs with total GSV stripping and 32% (7/22) in the limbs with restricted GSV stripping (P > .05). However, the recurrence rate in the tibial area was significantly lower in limbs subjected to GSV stripping, which was in compliance with the preoperative CDI (9/103, 9%) compared with those that had undergone GSV stripping that was not in agreement with the preoperative CDI (3/3, 100%; P < .005). Neurological examination at 1 month postoperatively, revealed SNI in 17 limbs (16%). However, at the 5-year neurological reassessment, we found that seven out of these limbs (40%) were alleviated from SNI adverse symptoms presenting only deficits in sensation. In addition, no significance was found concerning SNI between limbs subjected to total and restricted GSV stripping (16/84 vs 1/22; P > .05).
Though SNI may occur after both restricted and total GSV stripping, this does not influence limb disability since any related symptoms seem to regress in almost half of the limbs 5 years postoperatively. Additionally, it seems that recurrence could be reduced in the tibial area if the level of GSV stripping complies with the extent of the ultrosonographically proven GSV reflux. Therefore, the extent of GSV stripping should not be guided by the intent of avoiding SNI.
探讨在5年期间,剥脱膝下大隐静脉(GSV)段对静脉曲张复发的影响以及隐神经损伤(SNI)后引起的任何功能障碍。
对106条肢体(86例患者,64例女性,平均年龄46岁)进行了GSV剥脱术,剥脱至膝部或踝部水平,术后1个月和5年进行前瞻性随访,通过临床检查和彩色双功能超声成像(CDI)评估SNI和复发情况。在84条肢体(79%)中,GSV剥脱范围与术前CDI相符,这些肢体的GSV剥脱至踝部且完全消除了双功能超声证实的反流。此外,19条肢体(18%)由于远端GSV功能正常,剥脱仅限于膝下水平。相反,在3条肢体(3%)中,由于胫骨处无静脉曲张,剥脱范围不符合术前CDI,尽管整个GSV长度均有反流,但剥脱仅限于膝部水平。
术后5年,106条手术肢体中有24条(23%)出现总体复发。GSV完全剥脱的肢体复发率为20%(17/84),GSV部分剥脱的肢体复发率为32%(7/22)(P>.05)。然而,与术前CDI相符的GSV剥脱肢体的胫骨区域复发率显著低于不符合术前CDI的GSV剥脱肢体(9/103,9%对比3/3,100%;P<.005)。术后1个月的神经学检查显示,17条肢体(16%)存在SNI。然而,在5年的神经学重新评估中,我们发现其中7条肢体(40%)的SNI不良症状有所缓解,仅存在感觉缺陷。此外,GSV完全剥脱和部分剥脱的肢体之间在SNI方面无显著差异(16/84对比1/22;P>.05)。
尽管在GSV部分剥脱和完全剥脱后均可能发生SNI,但这并不影响肢体功能障碍,因为术后5年几乎一半的肢体中任何相关症状似乎都有所缓解。此外,如果GSV剥脱水平与超声证实的GSV反流范围相符,胫骨区域的复发似乎可以减少。因此,GSV剥脱范围不应以避免SNI为指导。