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Src family kinases and the MEK/ERK pathway in the regulation of myeloid differentiation and myeloid leukemogenesis.

作者信息

Johnson Daniel E

机构信息

Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, 5117 Centre Avenue, Pittsburgh, PA 15213-1863, USA.

出版信息

Adv Enzyme Regul. 2008;48:98-112. doi: 10.1016/j.advenzreg.2007.11.002. Epub 2007 Nov 19.

Abstract
摘要

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本文引用的文献

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Signal transduction pathways that contribute to myeloid differentiation.
Leukemia. 2007 Jul;21(7):1363-77. doi: 10.1038/sj.leu.2404690. Epub 2007 Apr 19.
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Adv Enzyme Regul. 2007;47:64-103. doi: 10.1016/j.advenzreg.2006.12.013. Epub 2007 Mar 26.
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Important therapeutic targets in chronic myelogenous leukemia.
Clin Cancer Res. 2007 Feb 15;13(4):1089-97. doi: 10.1158/1078-0432.CCR-06-2147.
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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.
Biochim Biophys Acta. 2007 Aug;1773(8):1263-84. doi: 10.1016/j.bbamcr.2006.10.001. Epub 2006 Oct 7.
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FLT3 mutations: biology and treatment.
Hematology Am Soc Hematol Educ Program. 2006:178-84. doi: 10.1182/asheducation-2006.1.178.
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MEK blockade converts AML differentiating response to retinoids into extensive apoptosis.
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