Zang H S
Changzheng Hospital, Second Military Medical College, Shanghai.
Zhonghua Wai Ke Za Zhi. 1991 Oct;29(10):596-8, 652.
The median and ulnar nerves of 30 rabbits were surgically severed and replanted in situ on the right side, but a little segment was resected and left alone on the left side. Periodical examination of the specimen under light and electron microscopes in 24 weeks showed that in the replanted group (right side) the nerve fibers were regularly arranged in order with constant polarity, and the Schwann' cells were intact without signs of neuroma. In the control group (lift side) however, typical neuroma was formed. 30 painful amputation stump neuroma (7 recurrent ones following repeated excisions) in 17 patients were treated by the same method used in the experiment. Follow-up examination within 6-48 months (32.6 mon. on average) showed good and excellent results in 90.0% the neuroma. Four different methods for repairing various neuromas were described, and the cause of the poor result in 2 cases was discussed.
对30只家兔的正中神经和尺神经进行手术切断并在右侧原位再植,但切除一小段并留置于左侧作为对照。在24周内定期对标本进行光镜和电镜检查,结果显示再植组(右侧)神经纤维排列规则,极性恒定,施万细胞完整,无神经瘤迹象。然而,对照组(左侧)形成了典型的神经瘤。采用实验中相同的方法治疗了17例患者的30个疼痛性截肢残端神经瘤(其中7个为反复切除后的复发性神经瘤)。在6至48个月(平均32.6个月)的随访检查中,90.0%的神经瘤效果良好或极佳。描述了四种修复各种神经瘤的不同方法,并讨论了2例效果不佳的原因。