[Effects of morphological changes in the middle ear mucosa on reparative processes in the neotympanic membrane in reconstructive sanative operation in patients with chronic otitis media].

A complex clinicomorphological examination was performed in 39 patients with chronic otitis media (OM) who had undergone reconstructive sanative surgery. The analysis of the results of the above examination provided information on efficacy of the original method of semiquantitative assessment of local cell reactivity and qualitative composition of tissue elements (content of lymphocytes, plasmocytes, fibroblasts; the degree of development of the capillaries, fibrosis, stasis, edema, inflammation activity by neutrophil count). A retrospective analysis of tympanic membrane graft retention depending on morphological intraoperative condition of the middle ear mucosa and retrotympanic compartments enables prognosis of tympanoplasty outcome in chronic OM.