Romanov I S, Odzharova A A, Rotin D L, Nechushkin M I
Vestn Otorinolaringol. 2007(6):14-7.
Twenty five patients with squamous cell oral cancer and without clinical evidence of regional cervical metastases have undergone 99mTc lymphoscintigraphy of cervical lymph nodes to localize the sentinel node 24 hours before surgery. Intraoperative localization of the sentinel node with gamma-probe (the probe was removed afterwords) was followed by operation on the primary focus and radical neck fat dissection. The removed tissues were examined histologically. The sentinel nodes were detected in 22 (88%) patients. A total number of the sentinel lymph nodes was 44. Six patients had metastases in the sentinel nodes, in 3 of them metastases were detected in the removed fat. The results of the study show that the technique is informative in localization of the sentinel lymph node.
25例口腔鳞状细胞癌患者,无区域颈部转移的临床证据,在手术前24小时接受了颈部淋巴结99mTc淋巴闪烁显像以定位前哨淋巴结。术中用γ探测器定位前哨淋巴结(之后移除探测器),随后对原发灶进行手术并进行根治性颈部脂肪清扫。切除的组织进行组织学检查。22例(88%)患者检测到前哨淋巴结。前哨淋巴结总数为44个。6例患者前哨淋巴结有转移,其中3例在切除的脂肪中检测到转移。研究结果表明,该技术在前哨淋巴结定位方面具有信息价值。