Joumaa Mouhammed, Graham David, Rosman Howard
St. John Hospital and Medical Center, 22101 Moross, Detroit, MI, 48236, USA.
J Invasive Cardiol. 2008 Jan;20(1):35-6.
Coarctation of the aorta is a complex vascular lesion that usually originates distal to the left subclavian artery. It accounts for 5-10% of all congenital cardiovascular malformations and carries a high morbidity and mortality risk. Symptoms depend on the severity of the disease and other coexisting anomalies. Early in life, diagnosis is usually based on significant symptoms and physical findings. Many patients remain asymptomatic until adulthood, with most being diagnosed in the 2nd or 3rd decade. In this case report, we present a late diagnosis of aortic coarctation with a bicuspid aortic valve in a 52-year-old female. Our patient was relatively asymptomatic until she presented with chest discomfort, fatigue and dyspnea in her fifth decade of life. Based on the clinical presentation and the markedly elevated gradient, the patient was referred for corrective therapy.
主动脉缩窄是一种复杂的血管病变,通常起源于左锁骨下动脉远端。它占所有先天性心血管畸形的5%-10%,具有较高的发病率和死亡率风险。症状取决于疾病的严重程度和其他并存的异常情况。在生命早期,诊断通常基于明显的症状和体格检查结果。许多患者直到成年仍无症状,大多数在二三十岁时被诊断出来。在本病例报告中,我们呈现了一名52岁女性主动脉缩窄合并二叶式主动脉瓣的晚期诊断病例。我们的患者在五十多岁出现胸部不适、疲劳和呼吸困难之前相对无症状。基于临床表现和明显升高的压差,该患者被转诊接受矫正治疗。