催眠药与阿片类麻醉药对中枢神经系统的相互作用，重点在于响应面模型。

Hypnotic and opioid anesthetic drug interactions on the CNS, focus on response surface modeling.

作者信息

Bouillon T W

机构信息

Department of Anesthesia, Insepital Bern, 3010, Bern, Switzerland.

出版信息

Handb Exp Pharmacol. 2008(182):471-87. doi: 10.1007/978-3-540-74806-9_22.

DOI:10.1007/978-3-540-74806-9_22

PMID:18175105

Abstract

This chapter will present the conceptual and applied approaches to capture the interaction of anesthetic hypnotic drugs with opioid drugs, as used in the clinical anesthetic state. The graphic and mathematical approaches used to capture hypnotic/opiate anesthetic drug interactions will be presented. This chapter is not a review article about interaction modeling, but focuses on specific drug interactions within a quite narrow field, anesthesia.

摘要

本章将介绍用于描述麻醉催眠药物与阿片类药物在临床麻醉状态下相互作用的概念性和应用性方法。还将介绍用于描述催眠/阿片类麻醉药物相互作用的图表和数学方法。本章不是一篇关于相互作用建模的综述文章，而是聚焦于麻醉这一相当狭窄领域内的特定药物相互作用。