Seropian E
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1976 Jan-Mar;25(1-2):17-22.
The present paper reports on the effect of prolonged microbial hyposensitization applied in 206 cases of microbial allergic asthma in comparison to 95 asthmatic patients of the same category in which this treatment was not applied; improvement was obtained in 78% of the former lot as against 17% in the latter. The quanlity of the improvement obtained and the dependence of the results upon the various diagnostic criteria used are discussed. Microbial hyposensitization has proved efficient in asthmatic patients although its mechanism of action is not yet known, nor the difference that exists from this point of view with the current microbial vaccination. The data obtained suggest that microbial hyposensitization acts by the mechanism of microbial vaccination in all the variants of infectious asthma.
本文报告了对206例微生物过敏性哮喘患者进行长期微生物减敏治疗的效果,并与95例未进行该治疗的同类哮喘患者作比较;前一组有78%的患者病情得到改善,而后一组只有17%。文中讨论了所取得的改善质量以及结果与所采用的各种诊断标准的相关性。微生物减敏治疗已证明对哮喘患者有效,尽管其作用机制尚不清楚,从这一点来看也不清楚与目前的微生物疫苗接种有何不同。所获得的数据表明,在感染性哮喘的所有变体中,微生物减敏治疗都是通过微生物疫苗接种的机制起作用的。