Lo Chung-Chin, Hsu Jenn-Jeih, Hsieh Ching-Chang, Hsieh T'sang-T'ang, Hung Tai-Ho
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Taiwan J Obstet Gynecol. 2007 Dec;46(4):389-94. doi: 10.1016/S1028-4559(08)60008-X.
To identify the risk factors for spontaneous preterm delivery before 34 weeks of gestation among Taiwanese women.
This retrospective cohort study involved 36,453 Taiwanese women who delivered between July 1990 and December 2003. Pregnancies complicated by multiple gestation, fetal anomalies, and iatrogenic preterm births due to maternal or fetal indications were excluded.
Five hundred and five spontaneous preterm deliveries (1.4%) were identified. Risk factors for early preterm delivery included a prior preterm delivery (odds ratio [OR], 16.5; 95% confidence interval [CI], 11.1-24.6), placental abruption (OR, 13.4; 95% CI, 9.4-19.2), history of fetal demise (OR, 11.8; 95% CI, 7.7-18.0), chorioamnionitis (OR, 10.5; 95% CI, 7.4-14.9), oligohydramnios (OR, 10.1; 95% CI, 6.7-15.3), history of abruption (OR, 7.9; 95% CI, 2.4-26.0), unmarried (OR, 6.2; 95% CI, 2.9-13.2), conception by reproductive technology (OR, 2.7; 95% CI, 1.4-5.5), maternal age less than 20 years (OR, 3.5; 95% CI, 1.8-6.7), maternal age greater than 34 years (OR, 1.6; 95% CI, 1.2-2.1), three or more abortions (OR, 1.6; 95% CI, 1.9-2.3), and premature rupture of membranes (OR, 1.6; 95% CI, 1.3-2.0).
Some of the risk factors for early preterm delivery among Taiwanese women were the same as those of other ethnic groups, whereas some of the other risk factors were different.
确定台湾女性妊娠34周前自发性早产的危险因素。
这项回顾性队列研究纳入了1990年7月至2003年12月期间分娩的36453名台湾女性。排除多胎妊娠、胎儿畸形以及因母体或胎儿指征导致的医源性早产。
共识别出505例自发性早产(1.4%)。早期早产的危险因素包括既往早产史(比值比[OR],16.5;95%置信区间[CI],11.1 - 24.6)、胎盘早剥(OR,13.4;95% CI,9.4 - 19.2)、胎儿死亡史(OR,11.8;95% CI,7.7 - 18.0)、绒毛膜羊膜炎(OR,10.5;95% CI,7.4 - 14.9)、羊水过少(OR,10.1;95% CI,6.7 - 15.3)、早剥史(OR,7.9;95% CI,2.4 - 26.0)、未婚(OR,6.2;95% CI,2.9 - 13.2)、通过生殖技术受孕(OR,2.7;95% CI,1.4 - 5.5)、母亲年龄小于20岁(OR,3.5;95% CI,1.8 - 6.7)、母亲年龄大于34岁(OR,1.6;95% CI,1.2 - 2.1)、三次或更多次流产(OR,1.6;95% CI,1.9 - 2.3)以及胎膜早破(OR,1.6;95% CI,1.3 - 2.0)。
台湾女性早期早产的一些危险因素与其他种族群体相同,而其他一些危险因素则不同。