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用涡度-流函数方法分析狭窄分叉动脉中的脉动血流。

Analysis of pulsatile blood flow in constricted bifurcated arteries with vorticity-stream function approach.

作者信息

Chakravarty S, Sen S

机构信息

Department of Mathematics, Visva-Bharati University, Santiniketan, India.

出版信息

J Med Eng Technol. 2008 Jan-Feb;32(1):10-22. doi: 10.1080/03091900600700822.

Abstract

This theoretical investigation deals with an analysis of pulsatile blood flow in a model bifurcated artery having a stenosis in the parent arterial lumen. The geometry of the bifurcated arterial segment with an implanted stenosis in the parent duct is given an appropriate mathematical shape with the introduction of suitable curvature at the lateral junction and the flow divider. The vascular wall deformability is duly accounted for although the development of atherosclerosis in the arteries reduces its elastic property to some extent. The streaming blood contained in the bifurcated artery is treated to be Newtonian. The flow dynamic analysis applies two-dimensional unsteady incompressible nonlinear Navier-Stokes equations rewritten in the vorticity-stream function formulation. Following a radial coordinate transformation, these equations are solved numerically by a finite difference scheme with the approximate choice of the inlet and boundary conditions in concert with the biophysical point of view. The final numerical results are highlighted at the end of the paper through the exhibition of the wall shear stress and several time-variant patterns of streamlines and vorticity contours of the flow phenomena, which are highly influenced by the severity of the stenosis and the angle of bifurcation. The applicability of the present model is thus established.

摘要

本理论研究涉及对具有狭窄的母动脉腔的分叉动脉模型中的脉动血流进行分析。通过在侧支连接处和分流器处引入适当的曲率,赋予了在母管中植入狭窄的分叉动脉段的几何形状以合适的数学形状。尽管动脉粥样硬化的发展在一定程度上降低了血管壁的弹性,但仍充分考虑了血管壁的可变形性。分叉动脉中包含的流动血液被视为牛顿流体。流动动力学分析应用以涡度 - 流函数形式重写的二维非定常不可压缩非线性纳维 - 斯托克斯方程。经过径向坐标变换后,这些方程通过有限差分格式进行数值求解,并结合生物物理观点对入口和边界条件进行近似选择。本文末尾通过展示壁面剪应力以及流动现象的流线和涡度轮廓的几种随时间变化的模式突出了最终的数值结果,这些结果受到狭窄严重程度和分叉角度的高度影响。从而确立了本模型的适用性。

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