Manipadam Marie Therese, Singh Reecha, Vijay Abraham
Department of General Pathology, Christian Medical College, Vellore, India.
APMIS. 2007 Dec;115(12):1450-3. doi: 10.1111/j.1600-0463.2007.00851.x.
We report a case of primary jejunal dedifferentiated liposarcoma presenting as a submucosal polyp mimicking a benign neoplasm. This is an extremely rare presentation. The histological feature of interest was the spindle cell lipoma-like appearance of the well-differentiated component. The use of MDM2 immunostaining in differentiating benign lipomatous tumours from well-differentiated liposarcomas is mentioned, which is of value especially in lipomatous tumours of the gut where ulcerated benign tumours can show varying degrees of atypia.
我们报告一例原发性空肠去分化脂肪肉瘤,表现为黏膜下息肉,酷似良性肿瘤。这是一种极其罕见的表现。有趣的组织学特征是高分化成分呈梭形细胞脂肪瘤样外观。文中提到了使用MDM2免疫染色来区分良性脂肪瘤性肿瘤和高分化脂肪肉瘤,这尤其在肠道脂肪瘤性肿瘤中具有价值,因为溃疡的良性肿瘤可表现出不同程度的异型性。