Hayes Alison J, Clarke Philip M, Glasziou Paul G, Simes R John, Drury Paul L, Keech Anthony C
School of Public Health, University of Sydney, NSW 2006 Australia.
Diabetes Care. 2008 Apr;31(4):795-7. doi: 10.2337/dc07-1391. Epub 2008 Jan 9.
To investigate whether self-rated health profiles compiled using the EuroQol group's visual analog scale (EQ VAS) are independent predictors of vascular events and major complications in people with type 2 diabetes after controlling for standard clinical risk factors.
The study is based on 7,348 individuals with a mean follow-up of 2.4 years after completing the EQ-5D questionnaire. We used Cox proportional hazards modeling to estimate hazard ratios associated with EQ VAS scores after controlling for baseline covariates: age, sex, smoking status, diabetes duration, A1C, systolic blood pressure, BMI, plasma lipids, and prior clinical history.
A 10-point higher EQ VAS score was associated with a 6% (95% CI 1-11) lower risk of vascular events and a 22% (95% CI 15-28) lower risk of diabetes complications.
Self-rated health profiles compiled using the EQ VAS provide valuable information on patient risk in addition to that determined from clinical risk factors alone.
在控制标准临床危险因素后,研究使用欧洲五维度健康量表视觉模拟评分法(EQ VAS)编制的自评健康概况是否为2型糖尿病患者血管事件和主要并发症的独立预测因素。
该研究基于7348名个体,在完成EQ - 5D问卷后平均随访2.4年。我们使用Cox比例风险模型来估计在控制基线协变量(年龄、性别、吸烟状况、糖尿病病程、糖化血红蛋白、收缩压、体重指数、血脂和既往临床病史)后与EQ VAS评分相关的风险比。
EQ VAS评分每高10分,血管事件风险降低6%(95%可信区间1 - 11),糖尿病并发症风险降低22%(95%可信区间15 - 28)。
使用EQ VAS编制的自评健康概况除了能提供仅由临床危险因素所确定的信息外,还能提供有关患者风险的有价值信息。