Kim Yonghyun, Nandakumar M P, Marten Mark R
Department of Chemical and Biochemical Engineering, University of Maryland Baltimore County (UMBC), 1000 Hilltop Circle, Baltimore, MD 21250, USA.
Brief Funct Genomic Proteomic. 2008 Mar;7(2):87-94. doi: 10.1093/bfgp/elm031. Epub 2008 Jan 10.
Aspergilli are an important genus of filamentous fungi that contribute to a multibillion dollar industry. Since many fungal genome sequencing were recently completed, it would be advantageous to profile their proteome to better understand the fungal cell factory. Here, we review proteomic data generated for the Aspergilli in recent years. Thus far, a combined total of 28 cell surface, 102 secreted and 139 intracellular proteins have been identified based on 10 different studies on Aspergillus proteomics. A summary proteome map highlighting identified proteins in major metabolic pathway is presented.
曲霉是丝状真菌的一个重要属,对一个价值数十亿美元的产业有重要影响。由于最近完成了许多真菌基因组测序,对其蛋白质组进行分析以更好地了解真菌细胞工厂将是有益的。在此,我们综述近年来针对曲霉产生的蛋白质组学数据。迄今为止,基于对曲霉蛋白质组学的10项不同研究,总共已鉴定出28种细胞表面蛋白、102种分泌蛋白和139种细胞内蛋白。本文呈现了一张总结性蛋白质组图谱,突出显示了主要代谢途径中已鉴定的蛋白质。