Enk Martin Johannes, Lima Anna Carolina Lustosa, Massara Cristiano Lara, Coelho Paulo Marcos Zech, Schall Virginia Torres
Laboratory of Schistosomiasis, Department of Scientific Support-Unit for Biostatistics, René Rachou Research Center/Oswaldo Cruz Foundation, Avenida Augusto de Lima 1715, Belo Horizonte, Minas Gerais, Brazil.
Am J Trop Med Hyg. 2008 Jan;78(1):140-6.
Results of stool examinations for infections with Schistosoma mansoni among schoolchildren, living in a village of Minas Gerais State, Brazil, were used as an indicator to identify schistosomiasis-positive individuals within the entire population. This new approach is based on dividing the community into schoolchildren, members of households of schistosomiasis-positive and -negative schoolchildren, and members of households without schoolchildren. Each subgroup was evaluated comparing different sampling efforts with the predetermined "gold standard" to find the best relationship between detection rate and sampling effort. Consequently these results were combined, and a proposal for a new strategy, valid for an entire community, was elaborated. This alternative approach during the screening process permits to treat a similar proportion of positives as detected with 6 Kato-Katz slides of 3 stool samples, with 3-fold reduced sampling effort, enhancing the efficiency of schistosomiasis control programs in low-endemic areas.
对居住在巴西米纳斯吉拉斯州一个村庄的学童进行曼氏血吸虫感染粪便检查的结果，被用作在整个人口中识别血吸虫病阳性个体的指标。这种新方法基于将社区分为学童、血吸虫病阳性和阴性学童家庭的成员以及无学童家庭的成员。对每个亚组进行评估，将不同的抽样工作量与预先确定的“金标准”进行比较，以找出检出率与抽样工作量之间的最佳关系。因此，将这些结果综合起来，制定了一项适用于整个社区的新策略提案。筛查过程中的这种替代方法允许以与3份粪便样本的6张加藤-卡茨玻片检测到的阳性比例相似的比例进行治疗，同时抽样工作量减少了三分之二，提高了低流行地区血吸虫病控制项目的效率。
