Hegeman J M, Doesborgh S J C, van Niel M C, van Megen H J G M
opleiding tot psychiater en werkzaam bij Meerkanten, Ermelo.
Tijdschr Psychiatr. 2008;50(1):23-31.
Electroconvulsive therapy (ECT) is an effective treatment for depressive disorders in adults and the elderly. For adolescents however, ect is still a controversial treatment because little research has been done into the efficacy and side effects of ECT in adolescents and because psychiatrists working with children and adolescents are relatively unfamiliar with this form of treatment.
To investigate the efficacy of ECT in adolescents who were treated in Meerkanten between 2000 and 2006 for a therapy-resistant depressive episode and/or suicidal behaviour.
Scores on the Hamilton Depression Rating Scale or the Montgomery-Asberg Depression Rating Scale before and after ECT were compared. The percentage improvement on the depression scales and the percentage of patients who showed an improvement of at least 60% on the scales in the group of adolescents were compared with the percentage improvement in a group of adults treated in Meerkanten.
One-third of the adolescent patients showed an improvement of 60% or more on these scales; the average improvement was 46%. ECT was found to be equally effective in adolescents and adults.
ECT is a successful form of treatment for one-third of adolescents with a severe therapy-resistant depressive episode; this is a clinically relevant result for these patients for whom no alternative treatments are available.
电休克疗法（ECT）是治疗成人及老年人抑郁症的一种有效方法。然而，对于青少年而言，ECT仍是一种存在争议的治疗方法，因为针对ECT在青少年中的疗效和副作用的研究较少，且从事儿童及青少年治疗工作的精神科医生对这种治疗形式相对不熟悉。
调查2000年至2006年期间在Meerkanten接受治疗的、患有难治性抑郁发作和/或自杀行为的青少年患者接受ECT治疗的疗效。
比较ECT治疗前后汉密尔顿抑郁量表（Hamilton Depression Rating Scale）或蒙哥马利-阿斯伯格抑郁量表（Montgomery-Asberg Depression Rating Scale）的评分。将青少年组中抑郁量表的改善百分比以及量表上显示至少改善60%的患者百分比，与在Meerkanten接受治疗的成年组的改善百分比进行比较。
三分之一的青少年患者在这些量表上显示出60%或更高的改善；平均改善率为46%。发现ECT在青少年和成人中同样有效。
ECT是三分之一患有严重难治性抑郁发作的青少年患者的一种成功治疗方式；对于这些没有其他可用治疗方法的患者来说，这是一个具有临床意义的结果。
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