Márquez-Monter H, Fuentes-Orozco R, Correa-Lemus I, Becker I
Unidad de Invest, Biomédica, C.M.N., I.M.S.S., México, D.F.
Arch Invest Med (Mex). 1991 Jan-Mar;22(1):75-8.
A spider monkey (Ateles geoffroyi) studied at the San Juan de Aragon Zoo died with symptoms of amoebic dysentery verified by coprologic investigation of the parasite, his female partner was cured with conventional antiamoebic treatment. At autopsy widespread ulcerations in the colon and multiple liver abscesses were found, containing trophozoites of Entamoeba histolytica. Both lesions were identical to those observed in human amoebiasis. A short review of the literature in nonhuman primates infections points out that the so-called spontaneous amoebiasis seen in colonies of captive monkeys, and transmission to their newborns within the same species of monkeys, have been in contact with humans. It is proposed that amoebiasis in monkeys should be considered as an excellent model for experimental studies on amoebiasis because other phylogenetically distant species have shown different pathology or are resistant to the infection. Also, it should raise concern that monkeys may become carriers of cysts and trophozoites of virulent strains of E. histolytica. Entamoeba histolytica DNA hybridization techniques should be considered for comparing genomic similarities with other protozoa, including the genera Amoeba to establish its pattern of evolution.
在圣胡安·德阿拉贡动物园研究的一只蜘蛛猴（Ateles geoffroyi）因寄生虫粪便学检查确诊为阿米巴痢疾症状而死亡，其雌性伴侣经传统抗阿米巴治疗后痊愈。尸检发现结肠广泛溃疡和多个肝脓肿，其中含有溶组织内阿米巴滋养体。这两种病变与人类阿米巴病中观察到的病变相同。对非人类灵长类动物感染文献的简短回顾指出，在圈养猴群中出现的所谓自发性阿米巴病，以及在同一猴种内传染给其新生儿，都与人类有接触。有人提出，猴类阿米巴病应被视为阿米巴病实验研究的一个极佳模型，因为其他系统发育距离较远的物种表现出不同的病理学特征或对感染具有抗性。此外，猴类可能成为溶组织内阿米巴强毒株囊肿和滋养体的携带者这一点也应引起关注。应考虑使用溶组织内阿米巴DNA杂交技术来比较与其他原生动物（包括变形虫属）的基因组相似性，以建立其进化模式。
