Macovei M, Popa C, Alexianu M E, Vulcan P
Clinic of Neurology, Hospital G. Marinescu, Bucharest, Romania.
Rom J Neurol Psychiatry. 1991 Jul-Dec;29(3-4):153-8.
The present study describes a patient, aged 72 yrs, with pontine crossed syndrome, displaying ipsilateral to the lesion a syndrome of cranial nerves V, VI, VII, VIII, on the right; a right neocerebellar syndrome; anhidrosis in the right hemibody; contralateral to the lesion: thermoalgic anesthesia with hyperhidrosis in the left hemibody. Concomitant with the pontine lesion, the patient developed torpid trophic ulcerations all over the right hemiface which, in the course of one year, became deformed, retractile, depigmented of hyperpigmented scars, the erosion being so deep at the level of the right nasal wing that the latter disappeared. This clinical picture developed in a patient with basilar invagination of 3 mm and left humeral micromelia. Eight cases of trigeminal torpid trophic ulceration associated with lesions of the brain stem are known till now, but association with vascular pontine lesion has not been described as yet. Etiopathogenic considerations are made.
本研究描述了一名72岁患有脑桥交叉综合征的患者,病变同侧出现右侧Ⅴ、Ⅵ、Ⅶ、Ⅷ颅神经综合征;右侧新小脑综合征;右侧半侧身体无汗;病变对侧:左侧半侧身体热痛性感觉缺失伴多汗。与脑桥病变同时出现的是,患者右侧半侧面部出现迟缓性营养性溃疡,在一年的病程中,这些溃疡变形、挛缩、出现色素脱失或色素沉着瘢痕,右侧鼻翼处的糜烂非常深以至于鼻翼消失。这种临床症状出现在一名患有3mm基底凹陷和左侧肱骨短小畸形的患者身上。迄今为止,已知8例三叉神经迟缓性营养性溃疡与脑干病变相关,但与脑桥血管病变的关联尚未见报道。本文进行了病因学方面的思考。