Cuvellier Jean-Christophe, Couttenier Frédéric, Joriot-Chekaf Sylvie, Vallée Louis
Department of Child Neurology, Pediatric Clinic, University Hospital, Lille, France.
Pediatr Neurol. 2008 Feb;38(2):93-8. doi: 10.1016/j.pediatrneurol.2007.10.001.
To characterize the clinical profile, comorbidity and aggravating factors, and outcomes, a consecutive series of 34 French children and adolescents with chronic daily headache was studied. Of 206 referred over an inclusive interval of 2 years for the evaluation of headaches, 34 merited a diagnosis of chronic daily headache, which was defined as persistent or daily headaches of at least 3 months in duration. The overwhelming majority were female (61.8%), with a mean age at diagnosis of 10.5+/-3.1 years (range, 2.9-14.8 years). According to the Silberstein-Lipton criteria, transformed migraine was the etiology in 61.8%, whereas according to the second edition of the International Classification of Headache Disorders, chronic migraine accounted for 50% of cases. Stressors were recognized in 82%. Analgesic abuse was evident in 52.9%. Of the 29 for whom follow-up information was available, headaches resolved or greatly improved in 93.1%. Children and adolescents with chronic daily headache are thus a small subset of children with headache seen in general ambulatory practice. They tend to be girls in the midteen years experiencing a transformed migraine complicated by analgesic abuse, suggesting potential preventability. Simple measures, which can include reassurance and analgesia education, can be expected to result in improvement and eventual resolution of headache symptoms.
为了描述临床特征、合并症、加重因素及预后,我们对34例法国慢性每日头痛的儿童和青少年进行了一项连续性研究。在2年的纳入期内转诊来评估头痛的206例患者中,34例符合慢性每日头痛的诊断标准,即持续或每日头痛至少3个月。绝大多数为女性(61.8%),诊断时的平均年龄为10.5±3.1岁(范围2.9 - 14.8岁)。根据西尔伯斯坦 - 利普顿标准,转化型偏头痛是病因的占61.8%,而根据《头痛疾病国际分类》第二版,慢性偏头痛占病例的50%。82%的患者存在应激源。52.9%的患者存在明显的镇痛药滥用。在有随访信息的29例患者中,93.1%的患者头痛缓解或明显改善。因此,慢性每日头痛的儿童和青少年是普通门诊中头痛儿童的一小部分。他们往往是十几岁的女孩,患有转化型偏头痛并伴有镇痛药滥用,提示可能具有可预防性。包括安慰和镇痛药教育在内的简单措施有望改善并最终消除头痛症状。