Masutani H, Takahashi H, Sando I, Sato H
Elizabeth McCullough Knowles Otopathology Laboratory, University of Pittsburgh School of Medicine, Pennsylvania.
Auris Nasus Larynx. 1991;18(4):351-7. doi: 10.1016/s0385-8146(12)80228-8.
The volume of the vestibular aqueduct was studied by a computer-aided volumetric method in 9 temporal bones with endolymphatic hydrops from individuals with Menière's disease (MD), 7 temporal bones with endolymphatic hydrops from individuals without a history of Meniere's disease (non-MD hydrops), and 10 normal temporal bones (controls) to investigate the cause of endolymphatic hydrops in both MD and non-MD hydrops. A hypoplastic vestibular aqueduct was found significantly more often in the MD group than in either the non-MD hydrops group (chi 2-test, chi 2 = 4.063, p less than 0.05) or the control group (chi 2-test, chi 2 = 6.363, p less than 0.05). The difference in volume between the non-MD hydrops group and the control group was not significant. It is speculated that a small vestibular aqueduct (presumably containing a small endolymphatic sac) might be a predisposing factor in Menière's disease. In contrast, in non-MD hydrops, there seems to be no correlation of endolymphatic hydrops with a hypoplastic vestibular aqueduct and endolymphatic sac.
采用计算机辅助容积测量法，对9例梅尼埃病（MD）患者的伴有内淋巴积水的颞骨、7例无梅尼埃病病史患者的伴有内淋巴积水的颞骨（非MD性积水）以及10例正常颞骨（对照组）的前庭导水管容积进行了研究，以探究MD和非MD性积水的内淋巴积水病因。结果发现，MD组前庭导水管发育不全的发生率显著高于非MD性积水组（卡方检验，χ² = 4.063，p < 0.05）或对照组（卡方检验，χ² = 6.363，p < 0.05）。非MD性积水组与对照组之间的容积差异不显著。推测前庭导水管较小（可能包含较小的内淋巴囊）可能是梅尼埃病的一个易感因素。相比之下，在非MD性积水中，内淋巴积水与前庭导水管和内淋巴囊发育不全似乎没有相关性。
