Berkley Eliza M F, Gill Geoffrey J, Moore Lisa E, Rayburn William F
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of New Mexico School of Medicine, Albuquerque, USA.
J Reprod Med. 2007 Dec;52(12):1103-6.
Gorham and Kasabach-Merritt syndrome are rare diagnoses that can complicate pregnancy by increasing the risk of pelvic fracture and consumptive coagulopathy, respectively.
A 23-year-old woman, gravida 2, para 0101, with a prenatal diagnosis of Gorham syndrome from her previous pregnancy was admitted at 32 weeks' gestation with severe back and flank pain. Computed tomographic findings revealed multiple lytic lesions of the pelvis in addition to large hemangiomas. Similar to her first pregnancy, she quickly developed consumptive coagulopathy and required prompt preterm delivery. The postoperative course was complicated by prolonged intensive care and multiple transfusions.
The consumptive coagulopathy associated with Gorham syndrome and secondary Kasabach-Merritt syndrome can mimic severe preeclampsia, especially when recurrent.
戈勒姆病和卡萨巴赫-梅里特综合征是罕见的诊断,分别会因增加骨盆骨折和消耗性凝血病的风险而使妊娠复杂化。
一名23岁女性,孕2产0101,因前次妊娠产前诊断为戈勒姆病,在妊娠32周时因严重的背部和侧腹疼痛入院。计算机断层扫描结果显示,除了巨大血管瘤外,骨盆还有多个溶骨性病变。与她的第一次妊娠相似,她很快出现了消耗性凝血病,需要迅速进行早产。术后病程因长时间的重症监护和多次输血而复杂化。
与戈勒姆病和继发性卡萨巴赫-梅里特综合征相关的消耗性凝血病可模仿重度子痫前期,尤其是复发时。