从科摩罗群岛传入马达加斯加的耐药疟原虫。
Drug-resistant malaria parasites introduced into Madagascar from Comoros Islands.
作者信息
Ménard Didier, Randrianarivo-Solofoniaina Armand Eugène, Ahmed Bedja Said, Jahevitra Martial, Andriantsoanirina Valérie, Rasolofomanana Justin Ranjalahy, Rabarijaona Léon Paul
机构信息
Institut Pasteur de Madagascar, Antananarivo, Madagascar.
出版信息
Emerg Infect Dis. 2007 Nov;13(11):1759-62. doi: 10.3201/eid1311.070235.
To determine risk for drug-resistant malaria parasites entering Madagascar from Comoros Islands, we screened travelers. For the 141 Plasmodium falciparum isolates detected by real-time PCR, frequency of mutant alleles of genes associated with resistance to chloroquine and pyrimethamine was high. International-level antimalarial policy and a regional antimalarial forum are needed.
为确定抗药疟原虫从科摩罗群岛进入马达加斯加的风险，我们对旅行者进行了筛查。对于通过实时PCR检测到的141株恶性疟原虫分离株，与氯喹和乙胺嘧啶耐药相关基因的突变等位基因频率很高。需要制定国际层面的抗疟政策和召开区域抗疟论坛。
Zotero 插件