Zisis Charalambos, Guillin Alexandra, Heyries Laurent, Lienne Pascal, D'Journo Xavier-Benoit, Doddoli Christophe, Giudicelli Roger, Thomas Pascal-Alexandre
University of the Mediterranean, Assistance Publique, Hôpitaux de Marseille, Marseille, France.
Eur J Cardiothorac Surg. 2008 Mar;33(3):451-6. doi: 10.1016/j.ejcts.2007.12.020. Epub 2008 Jan 24.
To examine retrospectively the patients of our department who had a self-expandable totally covered metal stent placed for oesophageal leak.
Patients hospitalised in our department for oesophageal cancer and/or oesophageal perforation between 2004 and 2006. All medical records were retrospectively reviewed. Seventy-two patients underwent oesophageal resection for oesophageal cancer and 16 were managed for oesophageal perforations.
Eight out of 72 patients submitted to resection for oesophageal cancer had postoperative leaks, while one patient developed tracheo-oesophageal fistula (TEF) due to prolonged mechanical ventilation. Six of them had stent placement in first intention, whereas two received the procedure after an unsuccessful repeat operation. The mean stent placement time was 18.4 days (SD=15.2 days), whereas the median was 14 days. The leak was managed efficiently by the stent in seven patients, whereas two patients needed repeat operations (one with TEF). The mean stent removal time was 56.8 days (SD=30.5 days) and the median was 40 days. None developed anastomotic stricture. On the other hand, three out of 16 patients with perforation had a stent, two of them for Boerhaave syndrome and one for iatrogenic rupture after bariatric surgery. One of them required the stent 17 days after surgical repair with excellent results, while the other two patients had the stent placed immediately, but still needed thoracotomy to control the leak.
Stent placement can prove very useful in the management of post-oesophagectomy anastomotic leaks, but its contribution needs to be evaluated with caution in cases of oesophageal perforations or TEF. Larger series and prospective comparative clinical trials could eventually clarify the role of stents in clinical practice of surgical patients.
回顾性研究在我科接受自膨式全覆膜金属支架置入术治疗食管瘘的患者。
回顾性分析2004年至2006年期间在我科住院治疗食管癌和/或食管穿孔的患者。对所有病历进行回顾性审查。72例患者因食管癌接受食管切除术,16例患者因食管穿孔接受治疗。
72例接受食管癌切除术的患者中有8例术后发生吻合口漏,1例患者因机械通气时间延长发生气管食管瘘(TEF)。其中6例一期置入支架,2例在再次手术失败后接受该治疗。平均支架置入时间为18.4天(标准差=15.2天),中位数为14天。7例患者的吻合口漏通过支架得到有效控制,2例患者需要再次手术(1例发生TEF)。平均支架取出时间为56.8天(标准差=30.5天),中位数为40天。均未发生吻合口狭窄。另一方面,16例穿孔患者中有3例置入了支架,其中2例因Boerhaave综合征,1例因减重手术后医源性破裂。其中1例患者在手术修复17天后需要置入支架,效果良好,另外2例患者立即置入支架,但仍需要开胸手术控制漏出。
支架置入术在食管切除术后吻合口漏的治疗中可能非常有用,但在食管穿孔或TEF病例中,其作用需要谨慎评估。更大规模的系列研究和前瞻性对比临床试验最终可能会阐明支架在外科患者临床实践中的作用。