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[非典型病原体在慢性阻塞性肺疾病感染加重中的作用]

[Role of atypical pathogens in infectious exacerbations of COPD].

作者信息

Taşbakan Mehmet Sezai, Sayiner Ayça Arzu, Sayiner Abdullah

机构信息

Department of Chest Diseases, Izmir Training and Research Hospital, Izmir, Turkey.

出版信息

Tuberk Toraks. 2007;55(4):336-41.

Abstract

Bacterial and viral infections are major causes of chronic obstructive pulmonary disease (COPD) exacerbations This study aimed to find out the frequency of typical and atypical pathogens in the etiology of COPD exacerbations, to evaluate the effect of these infections on the prognosis of the disease and their relationship with the history, clinical and laboratory findings of the patients. Typical agents were determined in 32.9% and atypical agents in in 37.1% of the patients. Atypical pathogens were more commonly isolated from younger patients with mild obstructive disease. There was no change in terms of response to therapy in typical and atypical pneumonia groups.

摘要

细菌和病毒感染是慢性阻塞性肺疾病(COPD)急性加重的主要原因。本研究旨在查明COPD急性加重病因中典型和非典型病原体的出现频率,评估这些感染对疾病预后的影响及其与患者病史、临床和实验室检查结果的关系。32.9%的患者检测出典型病原体,37.1%的患者检测出非典型病原体。非典型病原体更常见于患有轻度阻塞性疾病的年轻患者。典型和非典型肺炎组在治疗反应方面没有变化。

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