Duc Sylvain R, Pfirrmann Christian W A, Koch Peter P, Zanetti Marco, Hodler Juerg
Department of Radiology, University Hospital Balgrist, Zurich, Switzerland.
Radiology. 2008 Feb;246(2):526-35. doi: 10.1148/radiol.2462062092.
To prospectively evaluate the accuracy of magnetic resonance (MR) imaging of the knee performed by using a three-dimensional (3D) isovoxel sequence involving an acquisition time of approximately 3 minutes, with surgery as the reference standard.
The study was institutional review board approved. Written informed consent was obtained from all patients. Thirty knees of 29 patients (14 women, 15 men; mean age, 41 years) were prospectively examined by using a 3D isovoxel true fast imaging with steady-state precession (FISP) sequence with water excitation and secondary multiplanar reformations. All patients underwent arthroscopy within 12 days after true FISP MR imaging. Two blinded readers evaluated the MR images. Accuracy for detection of cartilage defects and anterior cruciate ligament (ACL) and meniscal tears, interobserver agreement, and intermethod agreement were calculated.
Overall sensitivity, specificity, and accuracy of isovoxel true FISP imaging for the diagnosis of cartilage defects were 45%, 83%, and 76%, respectively, for reader 1 and 63%, 82%, and 83%, respectively, for reader 2. Averaged (for readers 1 and 2) sensitivity, specificity, and accuracy of isovoxel true FISP imaging were, respectively, 80%, 95%, and 90% for diagnosis of ACL tear; 100%, 82%, and 90% for diagnosis of medial meniscal tear; and 83%, 83%, and 83% for diagnosis of lateral meniscal tear. The standard MR sequences used at the authors' institution had overall sensitivities, specificities, and accuracies of 39%, 83%, and 71%, respectively, for reader 1 and 37%, 85%, and 76%, respectively, for reader 2. Averaged sensitivity, specificity, and accuracy of the standard MR sequences were, respectively, 70%, 100%, and 90% for diagnosis of ACL tear; 96%, 77%, and 85% for diagnosis of medial meniscal tear; and 83%, 77%, and 78% for diagnosis of lateral meniscal tear.
The diagnostic performance of knee MR imaging performed by using a 3D water excitation isovoxel true FISP sequence and an imaging time of approximately 3 minutes is comparable to the diagnostic performance of the MR sequences used as standards at the authors' institution.
前瞻性评估采用三维(3D)等体素序列、采集时间约3分钟的膝关节磁共振(MR)成像的准确性,以手术作为参考标准。
本研究经机构审查委员会批准。所有患者均签署了书面知情同意书。对29例患者(14例女性,15例男性;平均年龄41岁)的30个膝关节采用3D等体素稳态进动快速成像(FISP)序列及水激励和二次多平面重建进行前瞻性检查。所有患者在进行FISP MR成像后12天内接受关节镜检查。两名盲法阅片者对MR图像进行评估。计算软骨缺损、前交叉韧带(ACL)和半月板撕裂的检测准确性、观察者间一致性和方法间一致性。
阅片者1对软骨缺损诊断的等体素FISP成像总体敏感性、特异性和准确性分别为45%、83%和76%,阅片者2分别为63%、82%和83%。等体素FISP成像(阅片者1和阅片者2平均)对ACL撕裂诊断的敏感性、特异性和准确性分别为80%、95%和90%;对内侧半月板撕裂诊断的分别为100%、82%和90%;对外侧半月板撕裂诊断的分别为83%、83%和83%。作者所在机构使用的标准MR序列,阅片者1的总体敏感性、特异性和准确性分别为39%、83%和71%,阅片者2分别为37%、85%和76%。标准MR序列(阅片者1和阅片者2平均)对ACL撕裂诊断的敏感性、特异性和准确性分别为70%、100%和90%;对内侧半月板撕裂诊断的分别为96%、77%和85%;对外侧半月板撕裂诊断的分别为83%、77%和78%。
采用3D水激励等体素FISP序列、成像时间约3分钟的膝关节MR成像诊断性能与作者所在机构用作标准的MR序列的诊断性能相当。