Schut Ewout S, de Gans Jan, van de Beek Diederik
Department of Neurology, Centre of Infection and Immunity Amsterdam (CINIMA), Academic Medical Centre, Amsterdam, The Netherlands.
Pract Neurol. 2008 Feb;8(1):8-23. doi: 10.1136/jnnp.2007.139725.
Despite the availability of effective antibiotics, vaccination programmes and skilled acute-care facilities, there is still a significant mortality and morbidity from bacterial meningitis. Neurologists are often called on to "rule out bacterial meningitis", which can be difficult with the history and physical examination alone. In this review the authors will discuss the epidemiology, diagnosis and treatment of acute community-acquired bacterial meningitis in adults, focussing particularly on the management of patients with neurological complications, and stressing the importance of adjunctive dexamethasone.
尽管有有效的抗生素、疫苗接种计划和技术娴熟的急性护理设施,但细菌性脑膜炎仍会导致显著的死亡率和发病率。神经科医生常常被要求“排除细菌性脑膜炎”,而仅依靠病史和体格检查往往很难做到。在这篇综述中,作者将讨论成人急性社区获得性细菌性脑膜炎的流行病学、诊断和治疗,尤其关注有神经并发症患者的管理,并强调辅助使用地塞米松的重要性。