Handa Uma, Garg Shailja, Mohan Harsh
Department of Pathology, Government Medical College and Hospital, Chandigarh, India.
Diagn Cytopathol. 2008 Mar;36(3):183-7. doi: 10.1002/dc.20792.
Human cysticercosis commonly manifests as subcutaneous and intramuscular nodules. The current study highlights the role of fine needle aspiration cytology (FNAC) in the diagnosis of subcutaneous cysticercosis. One hundred and twenty two patients with subcutaneous swellings, diagnosed as cysticercus or suspicious of parasitic inflammation on FNAC, were included in the present study. The relevant clinical data, cytomorphological findings, and histopathological findings, wherever available were evaluated. In 57 cases, a definite evidence of cysticercus was obtained in the form of fragments of parasite bladder wall, hooklets, or intact larva. Out of these, biopsy correlation was available in 10 cases, eight of which failed to reveal any parasite. In 65 cases, larval fragments could not be identified on aspirates, and the diagnosis of parasitic inflammation was suggested on the basis of other cytomorphological findings, which are discussed. In 22 of these cases, a biopsy correlation was available, which revealed definite parasitic elements in six cases and the remaining 16 cases were reported as suggestive of parasitic cysts. Thus, to conclude, FNAC is a reliable and cost effective procedure for the diagnosis of subcutaneous parasitic nodules. It obviates the need for a subsequent histopathological examination, as the parasite may not be demonstrated even on biopsy specimens.
人类囊尾蚴病通常表现为皮下和肌肉结节。本研究强调了细针穿刺细胞学检查（FNAC）在皮下囊尾蚴病诊断中的作用。本研究纳入了122例皮下肿胀患者，这些患者经FNAC诊断为囊尾蚴病或怀疑为寄生虫性炎症。对相关临床资料、细胞形态学发现以及可获得的组织病理学发现进行了评估。在57例病例中，以寄生虫囊壁碎片、小钩或完整幼虫的形式获得了囊尾蚴的明确证据。其中，10例有活检相关性，其中8例未发现任何寄生虫。在65例病例中，抽吸物中未发现幼虫碎片，并根据其他细胞形态学发现提示寄生虫性炎症诊断，对此进行了讨论。在这些病例中的22例有活检相关性，其中6例显示有明确的寄生虫成分，其余16例报告提示为寄生虫囊肿。因此，综上所述，FNAC是诊断皮下寄生虫结节的一种可靠且经济有效的方法。它无需后续的组织病理学检查，因为即使在活检标本上也可能无法显示寄生虫。
