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人工股臀皱襞成形术中使用的戈尔特斯补片排斥反应:病例系列

Rejection of goretex mesh used in prosthetic cruroplasty: a case series.

作者信息

Griffith P Sahle, Valenti Victor, Qurashi Kamran, Martinez-Isla Alberto

机构信息

Upper GI Unit, Ealing Hospital, London, UK.

出版信息

Int J Surg. 2008 Apr;6(2):106-9. doi: 10.1016/j.ijsu.2007.12.004. Epub 2008 Jan 30.

Abstract

INTRODUCTION

In recent years prosthetic cruroplasty with PTFE has been advocated as the optimal way to reduce hernia recurrence when repairing large hiatal hernia. However, we have found in our series a significant incidence of rejection and mesh erosion.

MATERIALS AND METHODS

Standard, tension-free ePTFE hiatal hernia repair was performed in 15 patients with large hiatal hernia. Three of these patients subsequently went on to develop complications with the mesh. Here we present these cases: 2 females and 1 male aged 84, 66 and 69 years, respectively. Each underwent prosthetic hiatal hernia repair using dual goretex mesh. After 7, 12, and 34 months each of the cases presented with dysphagia.

RESULTS

In all three of these cases initial endoscopy revealed narrowing at the lower end of the oesophagus, with inflammatory changes and erosion. In two of the cases, the mesh was noted to have eroded into the distal oesophagus, and in the third case relaparoscopy showed a peri-oesophageal collection including the mesh surrounded with fibrosis. Each of the complications was managed using minimally invasive techniques. In one instance the eroded mesh was removed by endoscopy without further complication. While in the second, due to the patient's age and comorbidities the eroded mesh was left in-situ and a covering stent was endoscopically sited. In the case of the peri-oesophageal collection, this was drained laparoscopically and the mesh was removed, with the patient making an excellent recovery. In each instance the patient's dysphagia was corrected and there was no recurrence of the hiatus hernia.

CONCLUSIONS

We conclude by acknowledging that in spite of the fact that Gore-Tex (ePTFE) is currently being recommended as one of the choice materials for the prosthetic reconstruction of the hiatus. Our experience suggests that it should be used with great caution in the peri-oesophageal region.

摘要

引言

近年来,有人主张使用聚四氟乙烯(PTFE)进行人工修补术是修复大型食管裂孔疝时降低疝复发率的最佳方法。然而,我们在自己的病例系列中发现了较高的排斥反应和补片侵蚀发生率。

材料与方法

对15例大型食管裂孔疝患者进行了标准的无张力ePTFE食管裂孔疝修补术。其中3例患者随后出现了补片相关并发症。在此我们介绍这些病例:2例女性和1例男性,年龄分别为84岁、66岁和69岁。每例均使用双层戈尔特斯补片进行人工食管裂孔疝修补术。7个月、12个月和34个月后,每例患者均出现吞咽困难。

结果

在所有这3例病例中,最初的内镜检查均显示食管下端狭窄,伴有炎症改变和糜烂。其中2例病例中,发现补片已侵蚀至食管远端,在第3例病例中,再次腹腔镜检查显示食管周围有积液,包括被纤维化包围的补片。每例并发症均采用微创技术处理。1例中,通过内镜切除了侵蚀的补片,未出现进一步并发症。而在第2例中,由于患者年龄和合并症,侵蚀的补片留在原位,并在内镜下放置了覆盖支架。对于食管周围积液的病例,通过腹腔镜引流并取出补片,患者恢复良好。在每种情况下,患者的吞咽困难均得到纠正,食管裂孔疝未复发。

结论

我们承认,尽管目前戈尔特斯(ePTFE)被推荐为食管裂孔人工重建的首选材料之一。但我们的经验表明,在食管周围区域应极其谨慎地使用。

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