Farooq Shegufta J, Gottlob Irene, Benskin Sherwin, Proudlock Frank A
University of Leicester, Ophthalmology Group, Faculty of Medicine and Biological Sciences, Leicester, UK.
Invest Ophthalmol Vis Sci. 2008 Feb;49(2):589-93. doi: 10.1167/iovs.07-0899.
The effect of aging on torsional optokinetic nystagmus (tOKN) is unknown. The authors investigated changes in tOKN associated with aging in a group of healthy subjects.
Monocular torsional eye movements were recorded from 30 subjects between 19 and 72 years of age. Constant-velocity rotary stimuli in clockwise and counterclockwise directions were used to elicit tOKN at 40 degrees /s and 400 degrees /s.
The number of subjects in whom tOKN could not be detected increased with age and was consistent in both directions of stimulation and at both angular velocities of stimulation.
tOKN appears to fail increasingly with age, in contrast to previous reports of horizontal and vertical OKN systems. This indicates that the ability to respond to rotary motion is more sensitive to the effects of aging.
衰老对视动性眼球震颤(tOKN)的影响尚不清楚。作者在一组健康受试者中研究了与衰老相关的tOKN变化。
记录了30名年龄在19至72岁之间的受试者的单眼扭转眼球运动。使用顺时针和逆时针方向的恒速旋转刺激,以40度/秒和400度/秒的速度诱发tOKN。
无法检测到tOKN的受试者数量随年龄增加,且在刺激的两个方向和两个刺激角速度下均一致。
与先前关于水平和垂直视动性眼球震颤系统的报道相反,tOKN似乎随着年龄增长而越来越多地失效。这表明对旋转运动作出反应的能力对衰老的影响更敏感。