Int J Cardiol. 2009 May 29;134(3):402-4. doi: 10.1016/j.ijcard.2007.12.014. Epub 2008 Jan 30.
Although matrix metalloproteinase (MMP) expression is found to be elevated after acute coronary syndrome (ACS), the slow elevation of MMP levels and the lack of clinical outcome data do not currently make MMPs useful biomarkers for therapeutic decision making or risk stratification in ACS. They do, however, remain an active area of investigation as a therapeutic target.
尽管在急性冠状动脉综合征(ACS)后发现基质金属蛋白酶(MMP)的表达升高,但 MMP 水平的缓慢升高和缺乏临床结果数据目前并未使 MMP 成为 ACS 治疗决策或风险分层的有用生物标志物。然而,它们仍然是一个活跃的研究领域,作为治疗靶点。