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妊娠期间表现为气胸的肺滑膜肉瘤

Pulmonary synovial sarcoma presenting as a pneumothorax during pregnancy.

作者信息

Esaka Emmanuel J, Celebrezze Jennifer U, Golde Steven H, Chiossi Giuseppe, Thomas Ronald L

机构信息

Department of Obstetrics and Gynecology, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.

出版信息

Obstet Gynecol. 2008 Feb;111(2 Pt 2):555-8. doi: 10.1097/01.AOG.0000286769.70432.de.

Abstract

BACKGROUND

Synovial sarcoma is a clinically rare, but morphologically well-defined neoplasm, which accounts for approximately 10% of all malignant soft-tissue tumors. The diagnosis can be established with clinical and imaging evaluations together with immunohistochemical, electron microscopy, and molecular genetic studies.

CASE

We describe a case of primary pulmonary synovial sarcoma presenting as a pneumothorax in a young woman at 34 weeks of gestation. Her persistent symptomatology ultimately led to a video-assisted thoracoscopy and thorascopic decortication. The diagnosis was established by pathology and immunohistochemistry of the cells, which were consistent with primary pulmonary synovial sarcoma.

CONCLUSION

Malignancies, even those as uncommon as primary synovial sarcoma, should be considered in the differential diagnosis of pneumothorax during pregnancy.

摘要

背景

滑膜肉瘤是一种临床罕见但形态学特征明确的肿瘤,约占所有恶性软组织肿瘤的10%。其诊断可通过临床和影像学评估,结合免疫组织化学、电子显微镜及分子遗传学研究来确立。

病例

我们描述了一例原发性肺滑膜肉瘤病例,该病例表现为一名34周妊娠的年轻女性发生气胸。她持续的症状最终导致了电视辅助胸腔镜检查及胸腔镜剥脱术。通过对细胞进行病理学和免疫组织化学检查确诊,结果与原发性肺滑膜肉瘤相符。

结论

在妊娠期间气胸的鉴别诊断中,应考虑到恶性肿瘤,即使是像原发性滑膜肉瘤这样罕见的肿瘤。

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