Vrigneaud Laurence, Lefèbvre Delphine, Daem Alexandre Olive, Lemaitre Vincent
Service d'Hémodialyse,Centre Hospitalier Général, Valenciennes, France.
Nephrol Ther. 2008 Apr;4(2):111-3. doi: 10.1016/j.nephro.2007.11.005. Epub 2008 Feb 20.
Lanthanum carbonate is a new nonaluminium, noncalcium phosphate binder. The drug is well-tolerated its side-effects seem comparable to those of other phosphate binders. The most frequent side-effects are gastrointestinal complications. Cerny [New England Journal of Medecine 355(2006)1160.] and Kunzendorf have recently reported another effect of lanthanum carbonate based on its radiographic characteristics. We report another case of opacification of the intestine with lanthanum carbonate which underlines some difficulties in the use of this new phosphate binder.
碳酸镧是一种新型的非铝、非钙磷酸盐结合剂。该药物耐受性良好,其副作用似乎与其他磷酸盐结合剂相当。最常见的副作用是胃肠道并发症。Cerny[《新英格兰医学杂志》355(2006)1160]和Kunzendorf最近根据其影像学特征报道了碳酸镧的另一种作用。我们报告了另一例使用碳酸镧导致肠道浑浊的病例,这凸显了使用这种新型磷酸盐结合剂时的一些困难。