Huang Yu-Hsun, Chu Hsiao-Sang, Hu Fung-Rong, Wang I-Jong, Hou Yu-Chi, Chen Wei-Li
Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Cornea. 2008 Jan;27(1):111-3. doi: 10.1097/ICO.0b013e318156d572.
To report an unusual case of advancing wavelike epitheliopathy that recurred at a site opposite to the initially affected site.
Single interventional case report. This report describes a 50-year-old woman who presented with advancing, wavelike epitheliopathy of her right eye that lasted 2 months.
Slit-lamp biomicroscopy revealed wavy, coarse, irregular epithelium extending from the upper limbus to the central cornea. Confocal microscopy revealed abnormal basal epithelial cells with a loss of cellular borders and hyperreflective nuclei. Application of 1% silver nitrate solution onto the superior limbus effectively treated this condition. However, wavy, irregular epithelium was observed 2 years later in the lower limbus.
Advancing wavelike epitheliopathy can occur from the lower limbus and recur from the opposite side of the initial presentation, even after successful treatment with 1% silver nitrate solution.
报告一例罕见的进行性波状上皮病变病例,该病变在最初受累部位的对侧复发。
单例介入病例报告。本报告描述了一名50岁女性,其右眼出现进行性波状上皮病变,持续2个月。
裂隙灯显微镜检查显示,从上角膜缘延伸至中央角膜的上皮呈波浪状、粗糙且不规则。共聚焦显微镜检查显示基底上皮细胞异常,细胞边界消失,细胞核高反射。在上角膜缘应用1%硝酸银溶液有效治疗了该病症。然而,2年后在下角膜缘观察到波浪状、不规则上皮。
即使在用1%硝酸银溶液成功治疗后,进行性波状上皮病变仍可从下角膜缘发生,并在最初出现部位的对侧复发。