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从初始表现的对侧出现复发性进行性波状上皮病变。

Recurrent advancing wavelike epitheliopathy from the opposite side of the initial presentation.

作者信息

Huang Yu-Hsun, Chu Hsiao-Sang, Hu Fung-Rong, Wang I-Jong, Hou Yu-Chi, Chen Wei-Li

机构信息

Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

Cornea. 2008 Jan;27(1):111-3. doi: 10.1097/ICO.0b013e318156d572.

Abstract

PURPOSE

To report an unusual case of advancing wavelike epitheliopathy that recurred at a site opposite to the initially affected site.

METHODS

Single interventional case report. This report describes a 50-year-old woman who presented with advancing, wavelike epitheliopathy of her right eye that lasted 2 months.

RESULTS

Slit-lamp biomicroscopy revealed wavy, coarse, irregular epithelium extending from the upper limbus to the central cornea. Confocal microscopy revealed abnormal basal epithelial cells with a loss of cellular borders and hyperreflective nuclei. Application of 1% silver nitrate solution onto the superior limbus effectively treated this condition. However, wavy, irregular epithelium was observed 2 years later in the lower limbus.

CONCLUSIONS

Advancing wavelike epitheliopathy can occur from the lower limbus and recur from the opposite side of the initial presentation, even after successful treatment with 1% silver nitrate solution.

摘要

目的

报告一例罕见的进行性波状上皮病变病例,该病变在最初受累部位的对侧复发。

方法

单例介入病例报告。本报告描述了一名50岁女性,其右眼出现进行性波状上皮病变,持续2个月。

结果

裂隙灯显微镜检查显示,从上角膜缘延伸至中央角膜的上皮呈波浪状、粗糙且不规则。共聚焦显微镜检查显示基底上皮细胞异常,细胞边界消失,细胞核高反射。在上角膜缘应用1%硝酸银溶液有效治疗了该病症。然而,2年后在下角膜缘观察到波浪状、不规则上皮。

结论

即使在用1%硝酸银溶液成功治疗后,进行性波状上皮病变仍可从下角膜缘发生,并在最初出现部位的对侧复发。

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