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对于在体肺分流手术创建后出现急性并发症的新生儿和婴儿,植入支架作为再次手术的替代方法。

Implantation of stents as an alternative to reoperation in neonates and infants with acute complications after surgical creation of a systemic-to-pulmonary arterial shunt.

作者信息

Kaestner Michael, Handke Ronald P, Photiadis Joachim, Sigler Matthias, Schneider Martin B E

机构信息

Department of Pediatric Cardiology and Congenital Heart Disease, Asklepiosklinik St. Augustin GmbH, Deutsches Kinderherzzentrum, Sankt Augustin, Germany.

出版信息

Cardiol Young. 2008 Apr;18(2):177-84. doi: 10.1017/S1047951108001959. Epub 2008 Feb 5.

DOI:10.1017/S1047951108001959
PMID:18252016
Abstract

Creation of a systemic-to-pulmonary shunt is still the firstline treatment in neonates with duct-dependent pulmonary circulation, or in patients with hypoplastic left heart syndrome as a part of the first stage of the Norwood sequence. Acute complications after such surgery, such as stenosis, thrombosis, or kinking, are potentially lifethreatening. These complications require immediate revision or exchange of the shunt. In this report, we discuss interventional treatment as an alternative to surgery in 5 patients with acute stenosis or complete occlusion of a shunt. The age of the patients ranged from 12 to 62 days, with a median of 30 days, and their weights ranged between 2.2 and 4.6 kilogrammes, with a median of 3.2 kilogrammes. In 3 patients, the shunts were central or of modified Blalock-Taussig type, while the 2 patients with hypoplastic left heart syndrome had shunts from the right ventricle to the pulmonary arteries. We implanted 6 coronary arterial and 2 peripheral stent systems. The diameter of the balloon used for implantation had a ratio to the shunt of 0.9. to 1. All shunts were successfully reopened by stenting. During follow-up, 3 patients underwent further procedures on an elective basis. We have one patient on the waiting list for further surgical intervention, but one patient died of septicaemia unrelated to the interventional procedure one month after implantation. In our limited experience, implantation of stents is an effective and long-lasting treatment for complications of shunts in an emergency situation.

摘要

对于患有依赖动脉导管的肺循环的新生儿,或作为诺伍德序列第一阶段一部分的左心发育不全综合征患者,建立体肺分流仍是一线治疗方法。此类手术后的急性并发症,如狭窄、血栓形成或扭结,可能危及生命。这些并发症需要立即对分流进行修正或更换。在本报告中,我们讨论了对5例分流急性狭窄或完全闭塞患者采用介入治疗作为手术替代方案的情况。患者年龄在12至62天之间,中位数为30天,体重在2.2至4.6千克之间,中位数为3.2千克。3例患者的分流为中心型或改良布莱洛克 - 陶西格型,而2例左心发育不全综合征患者的分流是从右心室至肺动脉。我们植入了6个冠状动脉支架系统和2个外周支架系统。用于植入的球囊直径与分流的比例为0.9至1。所有分流通过支架置入均成功重新开通。在随访期间,3例患者择期接受了进一步治疗。我们有1例患者在等待进一步的手术干预,但有1例患者在植入后1个月死于与介入手术无关的败血症。根据我们有限的经验,在紧急情况下,支架植入是治疗分流并发症的一种有效且持久的方法。

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The role of stents in the treatment of congenital heart disease: Current status and future perspectives.支架在先天性心脏病治疗中的作用:现状与未来展望。
Ann Pediatr Cardiol. 2009 Jan;2(1):3-23. doi: 10.4103/0974-2069.52802.