Jacobs J, Sena M, Fox N
Center for Economic Studies in Medicine, A Division of Pracon Consulting Services, Reston, Virginia 22091.
Diabet Med. 1991;8 Spec No:S23-9. doi: 10.1111/j.1464-5491.1991.tb02151.x.
Estimates of the cost of diabetes should take into account the development of complications. Patient records identified from the 1987 National Hospital Discharge Survey were used to evaluate the risk of hospitalization due to late complications. Hospitalization for diabetic nephropathy reached a peak of 6.74/1000 between the ages of 45 and 54 years, compared to 0.14 to 1.80/1000 in controls. Diabetic patients less than or equal to 45 years of age were 46 times more likely to be hospitalized due to neuropathy. The risk of cardiovascular complications is high, with a greater incidence of arterial than venous disorders. Diabetic patients were 22 times more likely to be admitted for skin ulcers/gangrene, 15 times more likely due to peripheral vascular disease, and 10 times due to atherosclerosis. The risk of cerebrovascular accident and heart disease was 6 to 10 times greater in diabetic patients. Seventy-five per cent of diabetic cardiovascular disorders are myocardial infarction or chronic ischaemia. Hospitalization from renal complications occurs at younger ages than in the general population. Ophthalmic complications increase with age. Diabetic complications account for 2% of the total hospital admissions in the US in 1987. The total cost of the treatment of late diabetic complications was estimated at +5091 million (cardiovascular 74%; renal diseases 10%; nephropathy 3.6%; ophthalmic disorders 1.5%; other unspecified diseases 10%).
糖尿病成本估算应考虑并发症的发展情况。利用从1987年全国医院出院调查中识别出的患者记录来评估因晚期并发症导致住院的风险。糖尿病肾病导致的住院率在45至54岁之间达到峰值,为6.74/1000,而对照组为0.14至1.80/1000。年龄小于或等于45岁的糖尿病患者因神经病变住院的可能性高出46倍。心血管并发症风险很高,动脉疾病的发病率高于静脉疾病。糖尿病患者因皮肤溃疡/坏疽入院的可能性高出22倍,因外周血管疾病高出15倍,因动脉粥样硬化高出10倍。糖尿病患者发生脑血管意外和心脏病的风险高出6至10倍。75%的糖尿病心血管疾病为心肌梗死或慢性缺血。肾脏并发症导致的住院发生年龄比一般人群更小。眼科并发症随年龄增加。1987年,糖尿病并发症占美国住院总数的2%。晚期糖尿病并发症的治疗总成本估计为5.091亿美元(心血管疾病占74%;肾脏疾病占10%;肾病占3.6%;眼科疾病占1.5%;其他未明确疾病占10%)。