氯霉素对狗牙根黑粉菌电子系统的影响。
Effect of chloramphenicol on the electron systems in Ustilago cynodontis.
作者信息
Durieu-Trautmann O, Tavlitzki J
出版信息
J Bacteriol. 1976 Sep;127(3):1063-9. doi: 10.1128/jb.127.3.1063-1069.1976.
The mycelial cells of Ustilago cynodontis possess at least two electron transport systems: a cyanide-sensitive cytochrome pathway, which represents the major route for electron transport, and an alternative cyanide-insensitive pathway, inhibited by salicylhydroxamic acid. In the presence of chloramphenicol in the culture medium, mycelial cells respire only by the alternatuve chain. The stable induced yeast-like cells, obtained by prolonged chloramphenicol treatment of the mycelial cells, respire as the untreated mycelial cells; this result indicates that the phenotypic change induced by chloramphenicol is not related to a modification of the respiratory system.
狗牙根黑粉菌的菌丝体细胞至少拥有两个电子传递系统
一条对氰化物敏感的细胞色素途径，它是电子传递的主要途径；另一条替代的对氰化物不敏感的途径，受水杨羟肟酸抑制。在培养基中存在氯霉素的情况下，菌丝体细胞仅通过替代途径进行呼吸。通过对菌丝体细胞进行长时间氯霉素处理获得的稳定诱导的酵母样细胞，其呼吸方式与未处理的菌丝体细胞相同；这一结果表明，氯霉素诱导的表型变化与呼吸系统的改变无关。
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