Modic椎体终板及骨髓改变：病理意义及其与腰椎背痛和节段性不稳定的关系
The modic vertebral endplate and marrow changes: pathologic significance and relation to low back pain and segmental instability of the lumbar spine.
作者信息
Rahme R, Moussa R
机构信息
Department of Neurosurgery, Saint-Joseph University and Hôtel-Dieu de France, Beirut, Lebanon.
出版信息
AJNR Am J Neuroradiol. 2008 May;29(5):838-42. doi: 10.3174/ajnr.A0925. Epub 2008 Feb 13.
Abstract
Two decades following their description, the significance of Modic vertebral endplate and marrow changes remains a matter of debate. These changes are closely related to the normal degenerative process affecting the lumbar spine, and their prevalence increases with age. However, the exact pathogenesis underlying these changes and their relation to segmental instability of the lumbar spine and to low back pain remain unclear. In this paper, we review the literature relevant to this topic and discuss the currently available evidence regarding the pathologic and clinical significance of Modic changes.
摘要
在对其进行描述后的二十年里，Modic椎体终板及骨髓改变的意义仍存在争议。这些改变与影响腰椎的正常退变过程密切相关，且其发生率随年龄增长而增加。然而，这些改变背后的确切发病机制及其与腰椎节段性不稳定和腰痛的关系仍不清楚。在本文中，我们回顾了与该主题相关的文献，并讨论了目前关于Modic改变的病理及临床意义的现有证据。
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