[致病性链球菌的脂磷壁酸和磷壁酸：结构、功能及其在病原体与机体相互作用中的作用]

[Lipoteichoic and teichoic acids of pathogenic streptococci: structure, functions, and role in interaction of the infectious agent with organism].

作者信息

Dmitrieva N F, Timofeev Iu M, Briko N I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 2007 Nov-Dec(6):100-7.

Abstract

Features of structure, localization, and function of teichoic (TA) and lipoteichoic acids (LPA) of gram-positive bacteria are shortly characterized. Structures of polymers obtained from Streptococcus pyogenes, S. pneumoniae, S. agalactiae are described. The role of TA and LPA of pathogenic streptococci in different phases of infectious process and requirements for biological activity of these molecules are discussed.

摘要

简要描述了革兰氏阳性菌的磷壁酸（TA）和脂磷壁酸（LPA）的结构、定位及功能特征。描述了从化脓性链球菌、肺炎链球菌、无乳链球菌获得的聚合物结构。讨论了致病性链球菌的TA和LPA在感染过程不同阶段的作用以及这些分子的生物活性要求。