Sumby Paul, Tart Anne H, Musser James M
Center for Molecular and Translational Hman Infectious Diseases Research, The Methodist Hospital Research Institute, Houston, TX, USA.
Methods Mol Biol. 2008;431:255-67. doi: 10.1007/978-1-60327-032-8_20.
This chapter describes methods for using non-human primates as a model of group A streptococcal (GAS) pharyngitis. This model has been used successfully to study host-pathogen interactions occurring during pharyngeal GAS infections. The protocol as described will compare two different GAS strains for their ability to cause clinical symptoms of pharyngitis.
本章描述了将非人灵长类动物用作A组链球菌(GAS)咽炎模型的方法。该模型已成功用于研究咽部GAS感染期间发生的宿主-病原体相互作用。所描述的方案将比较两种不同的GAS菌株引起咽炎临床症状的能力。