Bradley Melanie, Vincent Brian
School of Chemistry, University of Bristol, Bristol, BS8 1TS, United Kingdom.
Langmuir. 2008 Mar 18;24(6):2421-5. doi: 10.1021/la703327v. Epub 2008 Feb 23.
The use of microgel particles for controlled uptake and release of active species has great potential. The compatibility of microgel particles with their environment and the functionality of the particles can be achieved by modification of the core microgel through the addition of a shell. In this work, core-shell microgel particles, with a pH-responsive core (polyvinylpyridine) and a temperature-responsive shell (poly-N-isopropylacrylamide), have been prepared and characterized. The uptake and release of an anionic surfactant from the microgels has been investigated as a function of solution pH and temperature. The results indicate that electrostatic attraction between the anionic surfactant and the cationically charged core of the microgel particles is the dominant mechanism for absorption of the surfactant into the core-shell microgel particles.
使用微凝胶颗粒来控制活性物质的摄取和释放具有巨大潜力。通过添加壳层对核心微凝胶进行改性，可以实现微凝胶颗粒与其环境的相容性以及颗粒的功能性。在这项工作中，制备并表征了具有pH响应性核心（聚乙烯基吡啶）和温度响应性壳层（聚-N-异丙基丙烯酰胺）的核壳微凝胶颗粒。研究了微凝胶对阴离子表面活性剂的摄取和释放随溶液pH值和温度的变化情况。结果表明，阴离子表面活性剂与微凝胶颗粒带正电荷的核心之间的静电吸引是表面活性剂被吸收到核壳微凝胶颗粒中的主要机制。
