Yurumez Yusuf, Yavuz Yucel, Saglam Hayrettin, Durukan Polat, Ozkan Seda, Akdur Okhan, Yucel Murat
Department of Emergency Medicine, Kocatepe University Medical Faculty, Afyonkarahisar, Turkey.
J Emerg Med. 2009 Jan;36(1):39-42. doi: 10.1016/j.jemermed.2007.08.063. Epub 2008 Mar 4.
In this study, we evaluated 85 patients who presented to our Emergency Department with organophosphate (OP) poisoning and discuss their associated electrocardiographic (ECG) abnormalities. Over a period of 3 years, 85 patients with OP poisoning were included in this retrospective study. ECG analysis included the rate, rhythm, ST-T abnormalities, conduction defects, and measurement of PR and QT intervals. The mean age was 32.2 +/- 14.9 years. Sixty percent of the patients were female. The mean corrected QT interval (QTc interval) was 0.435 +/- 0.052 s. Prolongation of the QTc interval (55.5%) was the most common ECG abnormality, followed by sinus tachycardia (31.8%). Elevation of the ST segment and low amplitude T waves were seen in 15 cases (17.6%). Patients with OP poisoning might reveal ECG abnormalities such as QTc interval prolongation or non-specific ST-T changes. QTc interval prolongation cannot be used as a unique predictive factor in determining short-term prognosis in OP poisoning. We found no clear relation between OP poisoning-related malignant ventricular dysrhythmia and QTc interval.
在本研究中,我们评估了85例因有机磷(OP)中毒前来我院急诊科就诊的患者,并探讨了其相关的心电图(ECG)异常情况。在3年的时间里,85例OP中毒患者被纳入这项回顾性研究。ECG分析包括心率、心律、ST-T异常、传导缺陷以及PR和QT间期的测量。平均年龄为32.2±14.9岁。60%的患者为女性。平均校正QT间期(QTc间期)为0.435±0.052秒。QTc间期延长(55.5%)是最常见的ECG异常,其次是窦性心动过速(31.8%)。15例患者(17.6%)出现ST段抬高和T波低平。OP中毒患者可能会出现ECG异常,如QTc间期延长或非特异性ST-T改变。QTc间期延长不能作为判断OP中毒短期预后的唯一预测因素。我们发现OP中毒相关的恶性室性心律失常与QTc间期之间没有明确的关系。