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急性有机磷中毒的心电图表现

Electrocardiographic findings of acute organophosphate poisoning.

作者信息

Yurumez Yusuf, Yavuz Yucel, Saglam Hayrettin, Durukan Polat, Ozkan Seda, Akdur Okhan, Yucel Murat

机构信息

Department of Emergency Medicine, Kocatepe University Medical Faculty, Afyonkarahisar, Turkey.

出版信息

J Emerg Med. 2009 Jan;36(1):39-42. doi: 10.1016/j.jemermed.2007.08.063. Epub 2008 Mar 4.

Abstract

In this study, we evaluated 85 patients who presented to our Emergency Department with organophosphate (OP) poisoning and discuss their associated electrocardiographic (ECG) abnormalities. Over a period of 3 years, 85 patients with OP poisoning were included in this retrospective study. ECG analysis included the rate, rhythm, ST-T abnormalities, conduction defects, and measurement of PR and QT intervals. The mean age was 32.2 +/- 14.9 years. Sixty percent of the patients were female. The mean corrected QT interval (QTc interval) was 0.435 +/- 0.052 s. Prolongation of the QTc interval (55.5%) was the most common ECG abnormality, followed by sinus tachycardia (31.8%). Elevation of the ST segment and low amplitude T waves were seen in 15 cases (17.6%). Patients with OP poisoning might reveal ECG abnormalities such as QTc interval prolongation or non-specific ST-T changes. QTc interval prolongation cannot be used as a unique predictive factor in determining short-term prognosis in OP poisoning. We found no clear relation between OP poisoning-related malignant ventricular dysrhythmia and QTc interval.

摘要

在本研究中,我们评估了85例因有机磷(OP)中毒前来我院急诊科就诊的患者,并探讨了其相关的心电图(ECG)异常情况。在3年的时间里,85例OP中毒患者被纳入这项回顾性研究。ECG分析包括心率、心律、ST-T异常、传导缺陷以及PR和QT间期的测量。平均年龄为32.2±14.9岁。60%的患者为女性。平均校正QT间期(QTc间期)为0.435±0.052秒。QTc间期延长(55.5%)是最常见的ECG异常,其次是窦性心动过速(31.8%)。15例患者(17.6%)出现ST段抬高和T波低平。OP中毒患者可能会出现ECG异常,如QTc间期延长或非特异性ST-T改变。QTc间期延长不能作为判断OP中毒短期预后的唯一预测因素。我们发现OP中毒相关的恶性室性心律失常与QTc间期之间没有明确的关系。

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