Coullet Julien, Fournié Pierre, Malecaze François, Arné Jean-Louis
Dept of Ophthalmology, Purpan Hospital, Place Dr Baylac, 31059 Toulouse, France.
J Refract Surg. 2008 Feb;24(2):166-72. doi: 10.3928/1081597X-20080201-07.
To evaluate a new automated technique--microkeratome-assisted additive stromal keratoplasty (MASK)--for the management of keratoconus in eyes scheduled for surgery with clear cornea associated with total contact lens intolerance.
This non-comparative, interventional case series included four eyes of four patients with stage I and II keratoconus associated with total contact lens intolerance. The first step of the surgical procedure consisted of performing a nasal-hinged flap on the host cornea with a microkeratome. The second step consisted of extracting a stromal piano-powered disk from the donor's cornea using an artificial chamber. The 80-microm thick lamellar graft was punched with a 7.5-mm circular trephine and positioned beneath the flap. Corneal refractive surgery was scheduled for the end of the sixth postoperative month.
No corneal refractive surgery was performed after 6 months of follow-up. Only one eye gained five lines of best spectacle-corrected visual acuity (BSCVA). Among the other three eyes, two had unchanged BSCVA and one lost one line of BSCVA. At the end of surgery, mean corneal thickness was increased by 148.75 microm.
Microkeratome-assisted additive stromal keratoplasty appears to be a safe and straightforward surgical technique that preserves the host endothelium and avoids the need of an open-sky procedure. However, in our study, MASK is not considered as an alternative to penetrating or deep lamellar keratoplasty in the management of keratoconus with clear cornea because of imprecise anatomic and refractive outcomes.
评估一种新的自动化技术——微型角膜刀辅助的附加基质角膜移植术(MASK),用于治疗计划进行透明角膜手术且完全不耐受隐形眼镜的圆锥角膜患者。
本非对照性、介入性病例系列包括4例患有I期和II期圆锥角膜且完全不耐受隐形眼镜的患者的4只眼睛。手术过程的第一步是使用微型角膜刀在宿主角膜上制作一个鼻侧铰链瓣。第二步是使用人工前房从供体角膜中取出一个基质动力圆盘。用7.5毫米圆形环钻冲压出80微米厚的板层移植物,并将其置于瓣下。计划在术后第六个月末进行角膜屈光手术。
随访6个月后未进行角膜屈光手术。只有一只眼睛的最佳矫正视力(BSCVA)提高了5行。在其他三只眼中,两只眼睛的BSCVA没有变化,一只眼睛的BSCVA下降了1行。手术结束时,平均角膜厚度增加了148.75微米。
微型角膜刀辅助的附加基质角膜移植术似乎是一种安全、直接的手术技术,可保留宿主内皮细胞,避免进行开放式手术。然而,在我们的研究中,由于解剖和屈光结果不精确,MASK在治疗透明角膜圆锥角膜时不被视为穿透性或深板层角膜移植术的替代方法。