Simpson Colin R, Alford Karen, Williams David
Department of General Practice & Primary Care, Foresterhill Health Centre, The University of Aberdeen, UK.
Pharmacoepidemiol Drug Saf. 2008 Apr;17(4):397-400. doi: 10.1002/pds.1561.
To identify whether patients were prescribed the combination of aspirin-clopidogrel in primary care after the generally recommended 12-month period.
A population based cross-sectional study using data from 61 general practices (1st April 2003-31st March 2004).
691 patients (0.18% of total population) were prescribed aspirin-clopidogrel in combination. 27.78% of these patients had undergone coronary stenting or angioplasty and 34.30% were prescribed this combination for more than 1 year. 96 (13.9%) patients had a previous history of ischaemic stroke or transient ischaemic attack.
Patients were prescribed the combination of aspirin-clopidogrel beyond the generally accepted 12-month period, which may lead to increased safety and cost concerns.