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睾丸细针穿刺细胞学检查在不育症病例中的应用价值

Usefulness of testicular fine needle aspiration cytology in cases of infertility.

作者信息

Jain Manoj, Kumari Niraj, Rawat Amit, Gupta R K

机构信息

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.

出版信息

Indian J Pathol Microbiol. 2007 Oct;50(4):851-4.

Abstract

Testicular fine needle aspiration cytology (FNAC) is an important investigation in management of male infertility, especially to differentiate between obstructive and non obstructive causes of azoospermia. It is less invasive and associated with no or minimal complications. Nowadays when assisted fertilization techniques are being practiced, fibrosis after biopsy may further hamper in sperm extraction for intra cytoplasmic sperm injection (ICSI). Present study describes a detailed analysis of aspiration cytology in 546 cases and also compared 48 cases of testicular biopsies with cytology. The cytological diagnoses correlated well with histological diagnoses and helped in management of infertility. FNAC can help in management of surgical and medical causes of infertility and can save unnecessary expensive investigations in cases of sertoli cell only syndrome and atrophic patterns. FNAC in combination with semen analysis and serum follicle stimulating hormone levels are of great help in management of male infertility.

摘要

睾丸细针抽吸细胞学检查(FNAC)是男性不育症治疗中的一项重要检查,尤其有助于区分无精子症的梗阻性和非梗阻性病因。它侵入性较小,且并发症极少或没有。如今在辅助受精技术应用的情况下,活检后的纤维化可能会进一步妨碍卵胞浆内单精子注射(ICSI)的精子提取。本研究描述了对546例病例的抽吸细胞学详细分析,并将48例睾丸活检与细胞学进行了比较。细胞学诊断与组织学诊断相关性良好,有助于不育症的治疗。FNAC有助于处理不育症的手术和医学原因,在仅支持细胞综合征和萎缩模式的病例中可避免不必要的昂贵检查。FNAC与精液分析及血清促卵泡生成素水平相结合,对男性不育症的治疗有很大帮助。

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