Vottier Gaelle, Arsac Marie, Farnoux Caroline, Mariani-Kurkdjian Patricia, Baud Olivier, Aujard Yannick
Neonatal Intensive Care Unit, Children's Hospital Robert Debré Assistance Publique-Hôpitaux de Paris, Université Denis Diderot, Paris 7, France.
Acta Paediatr. 2008 Apr;97(4):505-8. doi: 10.1111/j.1651-2227.2008.00690.x. Epub 2008 Feb 27.
Congenital malaria is uncommon in nonendemic countries. We describe two cases involving neonates hospitalized with fever, anaemia and thrombocytopaenia. Thick and thin blood smears were positive for Plasmodium vivax (P. vivax) and P. ovale, respectively. These two cases were discussed regarding the literature and potential implications of HIV coinfection in the mother.
Consistent data in the literature suggest that peripheral blood films should be performed in HIV-positive women who travelled to an endemic area or with a history of malaria prior to gestation. With today's travelling patterns, congenital malaria should be considered as an important differential diagnosis of neonatal sepsis.
先天性疟疾在非流行国家并不常见。我们描述了两例新生儿病例,他们因发热、贫血和血小板减少症住院。厚血膜和薄血膜涂片分别检测到间日疟原虫和卵形疟原虫阳性。结合文献对这两例病例以及母亲合并感染艾滋病毒的潜在影响进行了讨论。
文献中的一致数据表明,对于前往流行地区或妊娠前有疟疾病史的艾滋病毒阳性女性,应进行外周血涂片检查。鉴于当今的旅行模式,先天性疟疾应被视为新生儿败血症的重要鉴别诊断。