Reeves David, Kennedy Anne, Fullwood Catherine, Bower Peter, Gardner Caroline, Gately Claire, Lee Victoria, Richardson Gerry, Rogers Anne
University of Manchester, National Primary Care Research and Development Centre, Manchester.
Br J Gen Pract. 2008 Mar;58(548):198-203. doi: 10.3399/bjgp08X277320.
In England, the Expert Patients Programme, a lay-led chronic disease self-management course, was developed to improve self-care support and skills. The course is designed for anyone with a self-defined long-term condition, and attracts a heterogeneous group of patients. A randomised controlled trial has demonstrated effectiveness in improving subjective health. However, it is not known whether particular patient characteristics predict the impact of the course.
To determine whether baseline characteristics predict clinical outcomes from attendance at a chronic disease self-management course; and to assess whether identification of such characteristics assists in targeting the course to individuals most likely to benefit.
A post-hoc subgroup analysis of data from a randomised controlled trial to explore predictors of three trial outcomes: self-efficacy, energy, and health-related quality of life.
Participants with self-defined long-term conditions (n = 629) were recruited from community settings in all 28 strategic health authorities in England.
Multiple regression was used to examine interactions between baseline variables and trial outcomes.
The predictors demonstrating significant interactions were: age and general health, and baseline values for self-efficacy, energy levels, and health-related quality of life.
Participants with lower self-efficacy and health-related quality of life at baseline demonstrated more positive health outcomes. The Expert Patients Programme may have a protective effect on health-related quality of life for patients with poor health and low confidence. Younger people benefited substantially more than older people. Results suggest that positive outcomes associated with the course will be demonstrated with a wide variety of patients, although it may be worthwhile encouraging attendance of younger patients, those lacking confidence, and those coping poorly with their condition.
在英国,由非专业人士主导的慢性病自我管理课程“专家患者计划”旨在改善自我护理支持和技能。该课程面向任何自我认定患有长期疾病的人,吸引了一群异质性的患者。一项随机对照试验已证明该课程在改善主观健康方面有效。然而,尚不清楚特定的患者特征是否能预测该课程的效果。
确定基线特征是否能预测参加慢性病自我管理课程后的临床结果;并评估识别这些特征是否有助于将该课程针对最可能受益的个体。
对一项随机对照试验的数据进行事后亚组分析,以探索三个试验结果的预测因素:自我效能感、精力和健康相关生活质量。
从英格兰所有28个战略卫生当局的社区环境中招募了自我认定患有长期疾病的参与者(n = 629)。
使用多元回归来检验基线变量与试验结果之间的相互作用。
显示出显著相互作用的预测因素为:年龄和总体健康状况,以及自我效能感、精力水平和健康相关生活质量的基线值。
基线时自我效能感较低和健康相关生活质量较差的参与者表现出更积极的健康结果。“专家患者计划”可能对健康状况不佳和信心不足的患者的健康相关生活质量具有保护作用。年轻人比老年人受益更多。结果表明,尽管鼓励年轻患者、缺乏信心的患者以及应对病情不佳的患者参加该课程可能是值得的,但该课程与各种患者相关的积极结果将会显现。