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囊性听神经瘤:58例患者的手术结果

Cystic acoustic neuromas: surgical outcome in a series of 58 patients.

作者信息

Sinha Sumit, Sharma B S

机构信息

Department of Neurosurgery, Neurosciences Centre, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

出版信息

J Clin Neurosci. 2008 May;15(5):511-5. doi: 10.1016/j.jocn.2007.01.007. Epub 2008 Mar 10.

Abstract

We aimed to analyze the clinical characteristics and surgical outcomes of surgically treated cystic acoustic neuromas, and to determine the prognostic significance of the presence of cystic components, by comparing surgical outcomes for solid and cystic tumors. A total of 58 patients (20.4%) with newly diagnosed cystic tumor were studied. The surgical outcome was analyzed in terms of extent of tumor removal, facial nerve preservation, morbidity and mortality; and was compared with that in patients with solid tumors. Facial nerve preservation rates were much better for solid tumors (82.7%) than for cystic tumors (67.9%). The extent of tumor removal was complete in 75.9% of patients with cystic tumors as compared with 90.2% for solid acoustic neuromas. Overall mortality was 8.6%. Cystic tumors differ from solid acoustic neuromas by having a rapid growth pattern, short clinical history and more frequent facial nerve involvement. They are associated with a poorer surgical outcome in terms of facial preservation and overall result.

摘要

我们旨在分析手术治疗的囊性听神经瘤的临床特征和手术结果,并通过比较实性和囊性肿瘤的手术结果,确定囊性成分存在的预后意义。共研究了58例新诊断为囊性肿瘤的患者(20.4%)。从肿瘤切除范围、面神经保留、发病率和死亡率方面分析手术结果,并与实性肿瘤患者的手术结果进行比较。实性肿瘤的面神经保留率(82.7%)远高于囊性肿瘤(67.9%)。囊性肿瘤患者的肿瘤切除率为75.9%,而实性听神经瘤为90.2%。总死亡率为8.6%。囊性肿瘤与实性听神经瘤不同,其生长模式迅速,临床病史短,面神经受累更频繁。就面部保留和总体结果而言,它们的手术结果较差。

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